Cellular signaling and dynamic interaction among genes result in stable phenotype
structures such as tumor or non tumor cells. Tumor and non-tumor cells often contain some …

Through cellular signaling networks, genes regulate the expression of other genes, which
eventually result in stable phenotype structures such as tumor or nontumor cells. Often …

This paper concerns a study indicating that the expression levels of genes in signaling
pathways can be modeled using a causal Bayesian network (BN) that is altered in tumorous …

High-throughput genomic technologies such as microarrays are now allowing scientists to
acquire extensive information on gene activities of thousands of genes in cells at any …

Cancer is a fetal and complex disease. Individual differences of the same cancer type or the
same patient at different stages of cancer development may require distinct treatments …

Modeling core of any signal and system processing and analysis. For example, an image
can be seen as a matrix (mathematical/deterministic model) and in this base for a …

Many biological research areas such as drug design require gene regulatory networks to
provide clear insight and understanding of the cellular process in living cells. This is …

Perturbations of gene regulatory networks are essentially responsible for oncogenesis.
Therefore, inferring the gene regulatory networks is a key step to overcoming cancer. In this …

Increased access to health care, and advances in education and technology have resulted
in a larger proportion of the population having longer life expectancy. The strong correlation …

An important problem in the study of cancer is the understanding of the heterogeneous
nature of the cell population. The clonal evolution of the tumor cells results in the tumors …