Maintenance of bovine oocytes in prophase of meiosis I by high [cAMP] i

H Aktas, MB Wheeler, CF Rosenkrans, NL First… - …, 1995 - rep.bioscientifica.com
The effects of high intracellular cAMP concentrations ([cAMP] i) on germinal vesicle
maintenance of bovine cumulus–oocyte complexes were investigated, using 8-bromo-3 …

[HTML][HTML] Participation of the adenosine salvage pathway and cyclic AMP modulation in oocyte energy metabolism

D Richani, CF Lavea, R Kanakkaparambil… - Scientific Reports, 2019 - nature.com
A follicular spike in cyclic AMP (cAMP) and its subsequent degradation to AMP promotes
oocyte maturation and ovulation. In vitro matured (IVM) oocytes do not receive the cAMP …

Resumption of rat oocyte meiosis is paralleled by a decrease in guanosine 3 ', 5'‐cyclic monophosphate (cGMP) and is inhibited by microinjection of cGMP

J Törnell, H Billig, T Hillensjö - Acta physiologica scandinavica, 1990 - Wiley Online Library
The aim of the present study was to measure the level of cyclic GMP (cGMP) compared with
the level of cyclic AMP (cAMP) in rat oocytes during resumption of meiosis I (oocyte …

Spontaneous maturation in vitro of cumulus-enclosed rat oocytes is inhibited by forskolin

N Dekel, E Aberdam, I Sherizly - Biology of Reproduction, 1984 - academic.oup.com
We have recently reported that the adenylate cyclase activator, forskolin, induces in the rat
ovarian follicle both cAMP accumulation and oocyte maturation. We demonstrate here, on …

A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes

SM Downs, ER Hudson, DG Hardie - Developmental biology, 2002 - Elsevier
Cyclic adenosine monophosphate (cAMP) has been implicated as an important regulator of
meiotic maturation in mammalian oocytes. A decrease in cAMP, brought about by the action …

[HTML][HTML] Rodent oocytes express an active adenylyl cyclase required for meiotic arrest

K Horner, G Livera, M Hinckley, K Trinh, D Storm… - Developmental …, 2003 - Elsevier
The intracellular levels of cAMP play a critical role in the meiotic arrest of mammalian
oocytes. However, it is debated whether this second messenger is produced endogenously …

Inhibition of maturation and metabolism in rat oocytes by cyclic AMP

C Magnusson, T Hillensjö - Journal of Experimental Zoology, 1977 - Wiley Online Library
It is known that dibutyryl cyclic AMP (dbcAMP) and theophylline inhibit the spontaneous
maturation of isolated mouse oocytes. The present study demonstrates that dbcAMP (0.01 …

The releasing action of calcium upon cyclic AMP‐dependent meiotic arrest in hamster oocytes

C Racowsky - Journal of Experimental Zoology, 1986 - Wiley Online Library
The effect of increasing cytoplasmic calcium on cyclic adenosine monophosphate (cAMP)‐
dependent meiotic arrest (% GV where GV is germinal vesicle) in hamster oocytes was …

Regulation of oocyte maturation. The role of cAMP.

N Dekel - Annals of the New York Academy of Sciences, 1988 - europepmc.org
We suggest that cAMP is a key molecule in regulation of oocyte maturation. In the small
follicle, tonic levels of cAMP are continuously transferred to the oocytes to maintain meiotic …

Meiotic state of bovine oocytes is regulated by interactions between cAMP, cumulus, and granulosa

H Aktas, ML Leibfried‐Rutledge… - Molecular Reproduction …, 2003 - Wiley Online Library
Bovine oocytes are arrested at the prophase of first meiotic cell cycle. Meiosis resumes in
oocytes of pre‐ovulatory follicles upon LH surge. However, oocytes from secondary follicles …