Temozolomide therapy in patients with aggressive pituitary adenomas or carcinomas
Temozolomide is effective in some patients with progressive pituitary adenoma or
carcinoma. We report a survey study of Italian patients treated with Temozolomide because …
carcinoma. We report a survey study of Italian patients treated with Temozolomide because …
Temozolomide treatment can improve overall survival in aggressive pituitary tumors and pituitary carcinomas
H Lasolle, C Cortet, F Castinetti, L Cloix… - European Journal of …, 2017 - academic.oup.com
Objectives Only few retrospective studies have reported an efficacy rate of temozolomide
(TMZ) in pituitary tumors (PT), all around 50%. However, the long-term survival of treated …
(TMZ) in pituitary tumors (PT), all around 50%. However, the long-term survival of treated …
Use of temozolomide in aggressive pituitary tumors: case report
S Mohammed, K Kovacs, W Mason, H Smyth… - …, 2009 - journals.lww.com
OBJECTIVE: The management of aggressive pituitary macroadenomas represents a
challenge to neurosurgeons. These tumors are very difficult to treat, owing mainly to their …
challenge to neurosurgeons. These tumors are very difficult to treat, owing mainly to their …
Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: a French multicenter experience
Context: To date only 18 patients with aggressive pituitary tumors or carcinomas treated with
temozolomide have been reported. Increased expression of O 6-methylguanine-DNA …
temozolomide have been reported. Increased expression of O 6-methylguanine-DNA …
Salvage therapy with temozolomide in patients with aggressive or metastatic pituitary adenomas: experience in six cases
M Losa, E Mazza, MR Terreni… - European Journal of …, 2010 - academic.oup.com
Objective The prognosis of either pituitary carcinoma or aggressive pituitary adenoma
resistant to standard therapies is poor. We assessed the efficacy of treatment with …
resistant to standard therapies is poor. We assessed the efficacy of treatment with …
Temozolomide therapy for aggressive pituitary tumors: results in a small series of patients from Argentina
OD Bruno, L Juárez-Allen… - International Journal …, 2015 - Wiley Online Library
We evaluated results of temozolomide (TMZ) therapy in six patients, aged 34–78 years,
presenting aggressive pituitary tumors. In all the patients tested O6‐methylguanine‐DNA …
presenting aggressive pituitary tumors. In all the patients tested O6‐methylguanine‐DNA …
How and when to use temozolomide to treat aggressive pituitary tumours
BC Whitelaw - Endocrine-related cancer, 2019 - erc.bioscientifica.com
Temozolomide is an oral chemotherapy used to treat aggressive pituitary tumours since
2006. It is inexpensive and well tolerated, the main side effects are fatigue, nausea and …
2006. It is inexpensive and well tolerated, the main side effects are fatigue, nausea and …
Temozolomide for aggressive ACTH pituitary tumors: failure of a second course of treatment
M Campderá, N Palacios, J Aller, R Magallón, P Martín… - Pituitary, 2016 - Springer
Introduction Temozolomide (TMZ) is an oral alkylating agent that has been used over the
past 8 years to treat aggressive pituitary tumors resistant to conventional therapy. To date …
past 8 years to treat aggressive pituitary tumors resistant to conventional therapy. To date …
Pituitary carcinomas and aggressive pituitary tumours: merits and pitfalls of temozolomide treatment
G Raverot, F Castinetti, E Jouanneau… - Clinical …, 2012 - Wiley Online Library
Pituitary carcinomas are rare, accounting for about 0· 2% of all pituitary tumours. They
represent a challenge to clinical practice in both diagnosis and treatment. They may present …
represent a challenge to clinical practice in both diagnosis and treatment. They may present …
Efficacy of temozolomide therapy in patients with aggressive pituitary adenomas and carcinomas—a German survey
U Elbelt, SM Schlaffer, M Buchfelder… - The Journal of …, 2020 - academic.oup.com
Context Despite growing evidence that temozolomide (TMZ) therapy is effective for the
treatment of aggressive pituitary tumors (APTs) or carcinomas (PCs), individual therapy …
treatment of aggressive pituitary tumors (APTs) or carcinomas (PCs), individual therapy …
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