Comprehensive metabolomics and network pharmacology to explore the mechanism of 5-hydroxymethyl furfural in the treatment of blood deficiency syndrome
W Zhang, N Cui, F Su, Y Wang, B Yang… - Frontiers in …, 2022 - frontiersin.org
Radix Rehmanniae (RR, from Radix Rehmanniae (Gaertn.) DC.) is a natural medicine used
in traditional Chinese medicine (TCM) since ancient times for the treatment of blood …
in traditional Chinese medicine (TCM) since ancient times for the treatment of blood …
Metabolomic strategies and biochemical analysis of the effect of processed Rehmanniae radix extract on a blood-deficient rat model
Y Wang, N Zhou, Z Shan, Y Ke, Z Liu, Z Liu… - … Medicine and Therapies, 2022 - Springer
Abstract Background Rehmanniae Radix (RR), an herb with numerous pharmacological
effects, is widely used in traditional Chinese medicine for the treatment of blood deficiency …
effects, is widely used in traditional Chinese medicine for the treatment of blood deficiency …
The mechanism of Renshen-Fuzi herb pair for treating heart failure—Integrating a cardiovascular pharmacological assessment with serum metabolomics
X Chen, Y Chen, S Xie, X Wang, Y Wu… - Frontiers in …, 2022 - frontiersin.org
Background: Renshen-Fuzi herb pair (RS-FZ) is often used in the clinical treatment of heart
failure (HF) and has a remarkable therapeutic effect. However, the mechanism of RS-FZ for …
failure (HF) and has a remarkable therapeutic effect. However, the mechanism of RS-FZ for …
The synergic renoprotective effect of Rehmanniae Radix Preparata and Corni Fructus on adenine-induced chronic kidney disease rats based on integrated plasma …
Z Zhang, L Yang, Y Wan, S Jiang, E Shang, D Qian… - Life Sciences, 2021 - Elsevier
Abstract Aims Rehmanniae Radix Preparata (RR) and Corni Fructus (CF) are commonly
used together for the treatment of chronic kidney disease (CKD) in the clinical practices for …
used together for the treatment of chronic kidney disease (CKD) in the clinical practices for …
Metabolomic study of the action mechanism of nourishing blood effect of fo-shou-san on blood deficiency mice
WX Li, MY Huang, YP Tang, JM Guo… - Yao xue xue bao …, 2013 - europepmc.org
The metabolic effect of Fo-Shou-San on blood deficiency mice was studied by using
metabolomic method. UPLC-QTOF/MS was used to analyze the plasma metabolome in …
metabolomic method. UPLC-QTOF/MS was used to analyze the plasma metabolome in …
Metabolomics coupled with integrative pharmacology reveal the protective effect of FangjiHuangqi Decoction against adriamycin-induced rat nephropathy model
WN Zhang, L Yang, SS He, XM Qin, AP Li - Journal of pharmaceutical and …, 2019 - Elsevier
With the development of the society, the number of people who got the nephrotic syndrome
(NS) is going up roughly. Therefore, finding a better way to treat NS is becoming a major …
(NS) is going up roughly. Therefore, finding a better way to treat NS is becoming a major …
Network pharmacology combined with metabolomics reveals the mechanism of Fuzi decoction against chronic heart failure in rats
T Gao, R Wang, H Zhang, F Zhao - Journal of Chromatography B, 2022 - Elsevier
Chronic heart failure (CHF) is the end stage of many severe heart diseases. Fuzi decoction
(FZD) originates from Zhang Zhongjing's Treatise on Febrile Diseases and is widely used in …
(FZD) originates from Zhang Zhongjing's Treatise on Febrile Diseases and is widely used in …
A UPLC-Q-TOF-MS-Based metabolomics approach to screen out active components in prepared rhubarb for its activity on noxious heat blood stasis syndrome
H Zhu, Y Duan, K Qin, J Jin, X Liu, B Cai - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Prepared rhubarb was obtained by steaming raw rhubarb with wine. Different
from raw rhubarb with a purgative effect, prepared rhubarb shows effects of promoting blood …
from raw rhubarb with a purgative effect, prepared rhubarb shows effects of promoting blood …
Integrated metabolomics and network pharmacology approach to explain possible action mechanisms of Xin-Sheng-Hua granule for treating anemia
HQ Pang, SJ Yue, YP Tang, YY Chen, YJ Tan… - Frontiers in …, 2018 - frontiersin.org
As a well-known traditional Chinese medicine (TCM) prescription, Xin-Sheng-Hua Granule
(XSHG) has been applied in China for more than 30 years to treat postpartum diseases …
(XSHG) has been applied in China for more than 30 years to treat postpartum diseases …
Serum, spleen metabolomics and gut microbiota reveals effect of catalpol on blood deficiency syndrome caused by cyclophosphamide and acetylphenylhydrazine
W Zhang, N Cui, F Su, Y Sun, B Li, Y Ren… - Frontiers in …, 2023 - frontiersin.org
Catalpol (CA), extracted from Rehmannia Radix, holds extensive promise as a natural
medicinal compound. This study employed 16S rRNA gene sequencing and combined …
medicinal compound. This study employed 16S rRNA gene sequencing and combined …