[HTML][HTML] Delineating inflammatory bowel disease through transcriptomic studies: current review of progress and evidence

SN Chan, EN Den Low, RAR Ali, NM Mokhtar - Intestinal research, 2018 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), which comprises of Crohn's disease and ulcerative
colitis, is an idiopathic relapsing and remitting disease in which the interplay of different …

Etiopathogenesis of inflammatory bowel disease: today and tomorrow

HSP de Souza - Current opinion in gastroenterology, 2017 - journals.lww.com
The continuing identification of several epigenetic, transcriptomic, proteomic, and
metabolomic alterations in patients with IBD reflects the complex nature of the disease and …

Characterisation of the circulating transcriptomic landscape in inflammatory bowel disease provides evidence for dysregulation of multiple transcription factors …

JK Nowak, AT Adams, R Kalla… - Journal of Crohn's …, 2022 - academic.oup.com
Aim To assess the pathobiological and translational importance of whole-blood
transcriptomic analysis in inflammatory bowel disease [IBD]. Methods We analysed whole …

Integrative analysis of transcriptomic and proteomic profiling in inflammatory bowel disease colon biopsies

L Jin, L Li, C Hu, J Paez-Cortez, Y Bi… - Inflammatory bowel …, 2019 - academic.oup.com
Background Crohn's disease (CD) and ulcerative colitis (UC) are intestinal chronic
inflammatory conditions characterized by altered epithelial barrier function and tissue …

Genomics and inflammatory bowel disease

S Schreiber, J Hampe - Current Opinion in Gastroenterology, 2000 - journals.lww.com
Genomic technologies offer new approaches to the investigation of etiology and
pathophysiology of inflammatory bowel disease (IBD). Several areas of application for these …

The genetic architecture of inflammatory bowel disease: past, present and future

I Cleynen, S Vermeire - Current opinion in gastroenterology, 2015 - journals.lww.com
Genetic, transcriptomic and epigenetic studies have offered exciting clues about IBD
pathogenesis but are unlikely to provide all answers. To fully grasp the function of disease …

Systematic analysis and characterization of long non-coding RNA genes in inflammatory bowel disease

R Velissari, M Ilieva, J Dao, HE Miller… - Briefings in …, 2023 - academic.oup.com
The cases of inflammatory bowel disease (IBD) are increasing rapidly around the world. Due
to the multifactorial causes of IBD, there is an urgent need to understand the pathogenesis of …

[HTML][HTML] Exploring potential biomarkers and therapeutic targets in inflammatory bowel disease: insights from a mega-analysis approach

E Stemmer, T Zahavi, M Kellerman… - Frontiers in …, 2024 - frontiersin.org
Background Understanding the molecular pathogenesis of inflammatory bowel disease
(IBD) has led to the discovery of new therapeutic targets that are more specific and effective …

Microbial genes and pathways in inflammatory bowel disease

M Schirmer, A Garner, H Vlamakis… - Nature Reviews …, 2019 - nature.com
Perturbations in the intestinal microbiome are implicated in inflammatory bowel disease
(IBD). Studies of treatment-naive patients have identified microbial taxa associated with …

Meta-analysis of IBD gut samples gene expression identifies specific markers of ileal and colonic diseases

K Perez, M Ngollo, K Rabinowitz… - Inflammatory Bowel …, 2022 - academic.oup.com
Abstract Background Inflammatory bowel diseases (IBDs) are characterized by chronic
inflammation and tissue damages in limited segments of the digestive tract. Pathogenesis in …