Clostridium difficile infection (CDI) remains a substantial burden on healthcare systems and
is likely to remain so given our reliance on antimicrobial therapies to treat bacterial …

Clostridium difficile is the most frequent cause of nosocomial antibiotic-associated diarrhea.
The incidence of C. difficile infection (CDI) has been rising worldwide with subsequent …

The pathogenesis of recurrent Clostridium difficile infection (CDI) is still poorly understood.
The risk of recurrence is approximately 20% after an initial CDI episode and dramatically …

The report of clindamycin-associated colitis in 1974 by Tedesco et al.[Ann Intern Med 81:
429–33] stimulated an intense search for the cause of this severe complication of antibiotic …

Clostridium difficile (C. difficile) is the most prevalent causative pathogen of healthcare‐
associated diarrhea. Notably, over the past 10 years, the number of Clostridium difficile …

Abstract Background Recurrent Clostridium difficile infection (rCDI) places a huge economic
and practical burden on healthcare facilities. Furthermore, rCDI may affect quality of life …

Clostridium difficile is the leading infectious cause of antibiotic‐associated diarrhea and
colitis. C. difficile infection (CDI) places a heavy burden on the healthcare system, with …

Background Clostridium difficile infection (CDI) remains a major health problem worldwide.
Antibiotic use, in general, and clindamycin and ciprofloxacin, in particular, have been …

The rapid evolution of antibiotic resistance in Clostridium difficile and the consequent effects
on prevention and treatment of C. difficile infections (CDIs) are matter of concern for public …

Clostridium difficile infection (CDI) is increasingly prevalent, dangerous and challenging to
prevent and manage. Despite intense national and international attention the incidence of …