Lipolytic response to glucose infusion in human subjects

RR Wolfe, EJ Peters - American Journal of Physiology …, 1987 - journals.physiology.org
We have determined the effect of various rates of glucose infusion on the rates of release of
glycerol (Ra glycerol), free fatty acids (Ra FFA), and on energy metabolism in normal human …

Regulation of triglyceride metabolism. IV. Hormonal regulation of lipolysis in adipose tissue

K Jaworski, E Sarkadi-Nagy… - American Journal …, 2007 - journals.physiology.org
Triacylglycerol (TAG) stored in adipose tissue can be rapidly mobilized by the hydrolytic
action of lipases, with the release of fatty acids (FA) that are used by other tissues during …

The antilipolytic action of insulin in obese subjects with resistance to its glucoregulatory action

BV HOWARD, I KLIMES, B VASQUEZ… - The Journal of …, 1984 - academic.oup.com
To compare the ability of insulin to regulate lipolysis in lean and obese subjects, free fatty
acid (FFA) suppression was compared in groups of six lean [body mass index, 25.7±1.1 …

[引用][C] Control of lipolysis and its relevance to development of obesity in man

P Amer - Diabetes/metabolism reviews, 1988 - Wiley Online Library
Obesity is a major health problem in the western world and its frequency is steadily
increasing. Although overeating and physical inactivity are probably the major causes of …

Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin

SD Mittelman, RN Bergman - American Journal of …, 2000 - journals.physiology.org
We have shown that insulin controls endogenous glucose production (EGP) indirectly, via
suppression of adipocyte lipolysis. Free fatty acids (FFA) and EGP are suppressed …

Insulin dose-response characteristics for suppression of glycerol release and conversion to glucose in humans

N Nurjhan, PJ Campbell, FP Kennedy, JM Miles… - Diabetes, 1986 - Am Diabetes Assoc
To compare the dose-response characteristics for suppression of lipolysis and suppression
of glucose production by insulin, 13 normal nonobese individuals were infused with insulin …

Insulin stimulation of adipose tissue lipoprotein lipase. Use of the euglycemic clamp technique.

CN Sadur, RH Eckel - The Journal of clinical investigation, 1982 - Am Soc Clin Investig
The role of insulin in the regulation of adipose tissue lipoprotein lipase activity in humans
was investigated in 11 normal subjects and compared with the effects of 0.9% saline …

Insulin responsiveness of adipose tissue lipoprotein lipase is delayed but preserved in obesity

UN SADUR, TJ YOST, RH ECKEL - The Journal of Clinical …, 1984 - academic.oup.com
Because increases in adipose tissue lipoprotein lipase (ATLPL) may be important in the
pathogenesis of obesity, the response of ATLPL to insulin during maintenance of …

Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal-weight humans

RV Farese Jr, TJ Yost, RH Eckel - Metabolism, 1991 - Elsevier
Eight normal-weight subjects (four men, four women) were studied to determine the relative
activities of lipoprotein lipase (LPL) in adipose tissue (ATLPL) and vastus lateralis skeletal …

Lipolysis during fasting. Decreased suppression by insulin and increased stimulation by epinephrine.

MD Jensen, MW Haymond, JE Gerich… - The Journal of …, 1987 - Am Soc Clin Investig
These studies were designed to determine whether the insulin resistance of fasting extends
to its antilipolytic effects and whether fasting enhances the lipolytic effects of adrenergic …