Mitochondria generate ATP essential for neuronal growth, function, and regeneration. Due
to their polarized structures, neurons face exceptional challenges to deliver mitochondria to …

Mitochondria are organelles responsible for bioenergetic metabolism, calcium homeostasis,
and signal transmission essential for neurons due to their high energy consumption …

Mitochondria are key cellular power plants essential for neuronal growth, survival, function,
and regeneration after injury. Given their unique morphological features, neurons face …

Axonal degeneration is a major contributor to neuronal dysfunction in many neurological
conditions and has additional roles in development. It can be triggered by divergent stimuli …

In this issue of Neuron, Han et al.(2016) and Cartoni et al.(2016) define a critical role of
mitochondrial transport for successful axon regeneration after injury and provide new …

Although neuronal regeneration is a highly energy-demanding process, axonal
mitochondrial transport progressively declines with maturation. Mature neurons typically fail …

Axon regeneration is essential to restore the nervous system after axon injury. However, the
neuronal cell biology that underlies axon regeneration is incompletely understood. Here we …

The unique polarization and high‐energy demand of neurons necessitates specialized
mechanisms to maintain energy homeostasis throughout the cell, particularly in the distal …

Over the last decade, mitochondrial dynamics beyond function during axon regeneration/
degeneration have received attention. Axons have an effective delivery system of …

Axonal homeostasis is maintained by processes that include cytoskeletal regulation, cargo
transport, synaptic activity, ionic balance, and energy supply. Several of these processes …