T2 Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosis
Rationale Considerable clinical heterogeneity in Idiopathic Pulmonary Fibrosis (IPF)
suggests the existence of multiple disease endotypes. Identifying these endotypes could …
suggests the existence of multiple disease endotypes. Identifying these endotypes could …
Pulmonary fibrosis in the era of stratified medicine
SK Mathai, CA Newton, DA Schwartz, CK Garcia - Thorax, 2016 - thorax.bmj.com
Both common and rare variants contribute to the genetic architecture of pulmonary fibrosis.
Genome-wide association studies have identified common variants, or those with a minor …
Genome-wide association studies have identified common variants, or those with a minor …
Integrative analyses for the identification of idiopathic pulmonary fibrosis-associated genes and shared loci with other diseases
Background Although genome-wide association studies (GWAS) have identified many
genomic regions associated with idiopathic pulmonary fibrosis (IPF), the causal genes and …
genomic regions associated with idiopathic pulmonary fibrosis (IPF), the causal genes and …
[HTML][HTML] Integrative analysis of lung molecular signatures reveals key drivers of idiopathic pulmonary fibrosis
SK Kim, SM Jung, KS Park, KJ Kim - BMC Pulmonary Medicine, 2021 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease with a high clinical
burden. The molecular signatures of IPF were analyzed to distinguish molecular subgroups …
burden. The molecular signatures of IPF were analyzed to distinguish molecular subgroups …
Genetics of idiopathic pulmonary fibrosis: from mechanistic pathways to personalised medicine
P Spagnolo, V Cottin - Journal of medical genetics, 2017 - jmg.bmj.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and ultimately fatal disorder for
which there is no cure. While the disease is by definition idiopathic, accumulating evidence …
which there is no cure. While the disease is by definition idiopathic, accumulating evidence …
Genetic and Lifestyle Risk Factors for Idiopathic Pulmonary Fibrosis: Greater Than the Sum of Its Parts
CA Newton - Chest, 2023 - journal.chestnet.org
Extensive efforts have provided clarity regarding the complex genetic architecture
underlying idiopathic pulmonary fibrosis (IPF). A multitude of genes and variants have been …
underlying idiopathic pulmonary fibrosis (IPF). A multitude of genes and variants have been …
Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis
Rationale: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterized by
scarring of the lung that is believed to result from an atypical response to injury of the …
scarring of the lung that is believed to result from an atypical response to injury of the …
Gene correlation network analysis to identify regulatory factors in idiopathic pulmonary fibrosis
Background Idiopathic pulmonary fibrosis (IPF) is a severe lung disease characterised by
extensive pathological changes. The objective for this study was to identify the gene network …
extensive pathological changes. The objective for this study was to identify the gene network …
[HTML][HTML] Detecting the molecular system signatures of idiopathic pulmonary fibrosis through integrated genomic analysis
I Gangwar, N Kumar Sharma, G Panzade, S Awasthi… - Scientific reports, 2017 - nature.com
Abstract Idiopathic Pulmonary Fibrosis (IPF) is an incurable progressive fibrotic disease of
the lungs. We currently lack a systematic understanding of IPF biology and a systems …
the lungs. We currently lack a systematic understanding of IPF biology and a systems …
[HTML][HTML] Consensus gene co-expression network analysis identifies novel genes associated with severity of fibrotic lung disease
Idiopathic pulmonary fibrosis (IPF) is a severe fibrotic lung disease characterized by
irreversible scarring of the lung parenchyma leading to dyspnea, progressive decline in lung …
irreversible scarring of the lung parenchyma leading to dyspnea, progressive decline in lung …