S98 Genome-wide association studies of pulmonary and non-pulmonary fibrosis

RJ Allen, E Joof, GM Massen, OC Leavy, G Parcesepe… - 2023 - thorax.bmj.com
Introduction Fibrosis is involved in up to one-third of deaths globally and can affect many
organ systems. Individuals with fibrosis in one organ may be more likely to develop fibrosis …

Integrative analyses of genes associated with idiopathic pulmonary fibrosis

H Wang, Q Xie, W Ou‐Yang… - Journal of Cellular …, 2019 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF), characterized by irreversible scarring and progressive
destruction of the lung tissue, is one of the most common types of idiopathic interstitial …

The Genetics of Pulmonary Fibrosis

SK Danoff, C Johnson - Idiopathic Pulmonary Fibrosis: A Comprehensive …, 2014 - Springer
The past two decades have been marked by a dramatic increase in the knowledge of the
genetics of human disease. The field of interstitial lung disease (ILD) genetics has expanded …

Idiopathic pulmonary fibrosis: phenotypes and comorbidities

A SHAH, CD FELL - Interstitial Lung Disease E-Book, 2017 - books.google.com
Idiopathic pulmonary fibrosis (IPF) is a progressive fatal disease of the lung with unknown
etiology and limited treatment options. It was once thought to be a slowly progressive …

Leveraging global multi-ancestry meta-analysis in the study of Idiopathic Pulmonary Fibrosis genetics

L Wain - 2022 - figshare.le.ac.uk
The research of rare and devastating orphan diseases, such as idiopathic pulmonary
fibrosis (IPF) has been limited by the rarity of the disease itself. The prognosis is poor—the …

European Respiratory Society statement on familial pulmonary fibrosis

R Borie, C Kannengiesser, K Antoniou… - European …, 2023 - Eur Respiratory Soc
Genetic predisposition to pulmonary fibrosis has been confirmed by the discovery of several
gene mutations that cause pulmonary fibrosis. Although genetic sequencing of familial …

P32 Using genetic information to define idiopathic pulmonary fibrosis in UK biobank

OC Leavy, RJ Allen, LM Kraven, AD Morgan, MD Tobin… - 2022 - thorax.bmj.com
Introduction Idiopathic pulmonary fibrosis (IPF) is a complex, heterogeneous fibrotic lung
disease with median survival of 3 years. IPF can be defined in population studies, such as …

Novel rare genetic variants in idiopathic pulmonary fibrosis

AS Kristof - European Respiratory Journal, 2020 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a rare disease of epithelial injury leading to persistent
fibrosis, remodelling of the lung parenchyma, and chronic respiratory failure [1]. IPF can be …

Identification and validation of potential biomarkers and pathways for idiopathic pulmonary fibrosis by comprehensive bioinformatics analysis

W Qian, X Cai, Q Qian, X Zhang - BioMed research …, 2021 - Wiley Online Library
Objective. Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible, high‐
mortality lung disease, but its pathogenesis is still unclear. Our purpose was to explore …

[HTML][HTML] Epigenomics of idiopathic pulmonary fibrosis: evaluating the first steps

EI Rabinovich, M Selman, N Kaminski - American journal of …, 2012 - atsjournals.org
2005; 288: L350–L358. 9. Martin C, Burdon PC, Bridger G, Gutierrez-Ramos JC, Williams
TJ, Rankin SM. Chemokines acting via CXCR2 and CXCR4 control the release of …