Human cytomegalovirus and immunopathology

JGP Sissons, AJ Carmichael… - Seminars in …, 2002 - search.proquest.com
Human cytomegalovirus (HCMV) is a ubiquitous human persistent virus, which causes
disease particularly in the setting of immunosuppression. This review deals with aspects of …

How understanding immunology contributes to managing CMV disease in immunosuppressed patients: now and in future

JGP Sissons, MR Wills - Medical microbiology and immunology, 2015 - Springer
Several decades of research on human cytomegalovirus (HCMV) and the principal
mammalian cytomegaloviruses which to varying degrees act as models of HCMV infection …

Human cytomegalovirus targets different subsets of antigen‐presenting cells with pathological consequences for host immunity: implications for immunosuppression …

S Varani, G Frascaroli, MP Landini… - Reviews in medical …, 2009 - Wiley Online Library
Human cytomegalovirus (HCMV) infection is a major cause of morbidity and mortality in
patients with an impaired immune system. The virus itself can cause transitory but significant …

The pathogenesis of human cytomegalovirus

P Griffiths, I Baraniak, M Reeves - The Journal of pathology, 2015 - Wiley Online Library
Human cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft
recipient and AIDS patients. More recently, it has been recognized as a pathogen for those …

The pathogenicity of human cytomegalovirus: an overview

ES Huang, TF Kowalik - Molecular aspects of human cytomegalovirus …, 1993 - Springer
Defining causality between an agent-be it a virus, bacteria, or chemical—and a disease is
the principal aim of biomedical research. Achievement of this lofty goal is hampered when …

[HTML][HTML] Pathogenesis of murine cytomegalovirus infection

A Krmpotic, I Bubic, B Polic, P Lucin, S Jonjic - Microbes and infection, 2003 - Elsevier
Infection of mice with murine cytomegalovirus (MCMV) is an established model for studying
human cytomegalovirus (HCMV) infection. Similarly to HCMV infection, pathological …

Cytomegalovirus—its cellular immunology and biology

JGP Sissons, LK Borysiewicz, B Rodgers, D Scott - Immunology today, 1986 - cell.com
The biology of persistent virus infections presents many intriguing questions, which extend
well beyond classical virology into molecular and cell biology and immunology. Here …

Human cytomegalovirus escape from immune detection

S Michelson - Intervirology, 2000 - karger.com
Human cytomegalovirus (CMV) has devised numerous means of escaping immune
surveillance. The CMV genome encodes at least 4 genes involved in downregulating …

Murine cytomegalovirus and other herpesviruses

GR Shellam, AJ Redwood, LM Smith… - The mouse in biomedical …, 2007 - Elsevier
Publisher Summary Murine cytomegalovirus (MCMV) is a very well studied virus of
laboratory mice. The discovery of the cytomegaloviruses had its origins in early studies of …

Cytomegalovirus: where have we been and where are we going?

TC Merigan, S Resta - Reviews of Infectious Diseases, 1990 - academic.oup.com
Nearly 30 years have elapsed since Rowe and Weller and their colleagues discovered
human cytomegalovirus (CMV). Because of its complex structure, long replicative cycle, low …