Extracellular matrix as a biological scaffold material: Structure and function

SF Badylak, DO Freytes, TW Gilbert - Acta biomaterialia, 2009 - Elsevier
Biological scaffold materials derived from the extracellular matrix (ECM) of intact mammalian
tissues have been successfully used in a variety of tissue engineering/regenerative …

The extracellular matrix as a biologic scaffold material

SF Badylak - Biomaterials, 2007 - Elsevier
Biologic scaffolds composed of naturally occurring extracellular matrix (ECM) have received
significant attention for their potential therapeutic applications. The full potential of the ability …

Extracellular matrix-based materials for regenerative medicine

GS Hussey, JL Dziki, SF Badylak - Nature Reviews Materials, 2018 - nature.com
In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …

Extracellular matrix-based biomaterials and their influence upon cell behavior

MC Cramer, SF Badylak - Annals of biomedical engineering, 2020 - Springer
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

[HTML][HTML] Preparation and use of decellularized extracellular matrix for tissue engineering

AD McInnes, MAJ Moser, X Chen - Journal of functional biomaterials, 2022 - mdpi.com
The multidisciplinary fields of tissue engineering and regenerative medicine have the
potential to revolutionize the practise of medicine through the abilities to repair, regenerate …

Extracellular matrix as an inductive scaffold for functional tissue reconstruction

BN Brown, SF Badylak - Translational Research, 2014 - Elsevier
The extracellular matrix (ECM) is a meshwork of both structural and functional proteins
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …

Biologic Scaffolds for Regenerative Medicine: Mechanisms of In vivo Remodeling

R Londono, SF Badylak - Annals of biomedical engineering, 2015 - Springer
Successful regenerative medicine strategies for functional tissue reconstruction include the
in situ placement of acellular materials composed of the extracellular matrix (ECM) or …

Extracellular matrix-based biomaterial scaffolds and the host response

JM Aamodt, DW Grainger - Biomaterials, 2016 - Elsevier
Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …

Decellularized matrices for tissue engineering

T Hoshiba, H Lu, N Kawazoe… - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Biomimetic scaffolds and substrates of extracellular matrices (ECMs)
play an important role in the regulation of cell function and in the guidance of new tissue …

Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance

TJ Keane, IT Swinehart, SF Badylak - Methods, 2015 - Elsevier
Biologic scaffolds composed of extracellular matrix (ECM) are widely used in both preclinical
animal studies and in many clinical applications to repair and reconstruct tissues. Recently …