Pharmacophore-based techniques currently are an integral part of many computer-aided
drug design workflows and have been successfully and extensively applied for tasks such …

Pharmacophore‐based techniques are nowadays an important part of many computer‐
aided drug design workflows and have been successfully applied for tasks such as virtual …

Pharmacophore approaches have become one of the major tools in drug discovery after the
past century's development. Various ligand-based and structure-based methods have been …

Pharmacophore modeling is a successful yet very diverse subfield of computer-aided drug
design. The concept of the pharmacophore has been widely applied to the rational design of …

With computer-aided drug design established as an integral part of the lead discovery and
optimization process, pharmacophores have become a focal point for conceptualizing and …

This chapter reviews theory related to pharmacophore models and guide the user through
six essential workflows using LigandScout: structure‐based pharmacophore modeling …

The pharmacophore concept in modern drug research is highlighted and the most important
use examples and success stories are reviewed. These include papers from method …

With the reliable use of computer simulations in scientific research, it is possible to achieve
significant increases in productivity as well as a reduction in research costs compared with …

A pharmacophore describes the framework of molecular features that are vital for the
biological activity of a compound. Pharmacophore models are built by using the structural …

This chapter is a review of the most recent developments in the field of pharmacophore
modeling, covering both methodology and application. Pharmacophore-based virtual …