▪ Abstract The compartmentation of eukaryotic cells requires all nuclear proteins to be
imported from the cytoplasm, whereas, for example, transfer RNAs, messenger RNAs, and …

Nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs) and is
mediated by saturable transport receptors that shuttle between the nucleus and cytoplasm …

In eukaryotes, the nuclear membrane provides a physical barrier to the passive diffusion of
macromolecules from and into the cytoplasm. Nucleocytoplasmic traffic occurs through …

Nucleocytoplasmic transport is an essential process in eukaryotes. The molecular
mechanisms underlying nuclear transport that involve the nuclear transport receptor, small …

Importin β family transport receptors shuttle between the nucleus and the cytoplasm and
mediate transport of macromolecules through nuclear pore complexes (NPCs). The …

In eukaryotic cells, cell functions are maintained in an orderly manner through the
continuous traffic of various proteins between the cell nucleus and the cytoplasm. The …

Proteins, RNAs and even large macromolecular complexes are transported into and out of
nuclei with remarkable rapidity and specificity. Nucleocytoplasmic transport must therefore …

Every minute, several million protein and RNA molecules must be transported between the
cytoplasm and the nucleus of a eukaryotic cell. The characterization of mediators, receptors …

Macromolecules enter or leave the nucleus by using nuclear localization signals (NLS), or
nuclear export signals (NES), respectively. Different types of NLS and NES are recognized …

The presence of the nuclear envelope necessitates the movement of proteins and RNAs
between the nucleus and the cytoplasm. Elaborate cellular machinery exists to promote the …