Transport of proteins into and out of the nucleus occurs through nuclear pore complexes
(NPCs) and is mediated by the interaction of transport factors with nucleoporins at the NPC …

Eukaryotic cells export several different classes of RNA molecule from the nucleus, where
they are transcribed, to the cytoplasm, where the majority participate in different aspects of …

Background: Transport of macromolecules between the nucleus and cytoplasm of eukaryotic
cells is mediated by nuclear import and export receptors. The receptors identified to date are …

The nuclear pore complex is the gateway for protein and RNA transport between the
cytoplasm and nucleus. Recent work has characterized signals and components involved in …

SUMMARY A defining characteristic of eukaryotic cells is the possession of a nuclear
envelope. Transport of macromolecules between the nuclear and cytoplasmic compartments …

Eukaryotic cells are equipped with a machinery charged with the responsibility of
transporting a vast number of molecules in and out of the nucleus in a rapid, accurate, and …

Previous work has shown that the transport of some small protein cargoes through the
nuclear pore complex (NPC) can occur in vitro in the absence of nucleoside triphosphate …

The past two years have seen a significant increase in our understanding of nuclear protein
import. Five cytosolic import factors have been identified, two of which have been shown to …

A striking property of nuclear pore complexes is their ability to mediate bi-directional
nucleocytoplasmic traffic of proteins and RNAs. In the past year, several new nuclear pore …

Recent progress indicates that there are multiple pathways of nucleocytoplasmic transport
which involve specific targeting sequences, such as nuclear localization sequences (NLSs) …