[HTML][HTML] Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis

S Nakielny, G Dreyfuss - Current biology, 1998 - cell.com
Background: Nuclear protein import and export are mediated by receptor proteins that
recognize nuclear localization sequences (NLSs) or nuclear export sequences (NESs) and …

Nucleocytoplasmic transport: cargo trafficking across the border

K Weis - Current opinion in cell biology, 2002 - Elsevier
Transport of macromolecules between the cytoplasm and the nucleus is mediated by at least
three different classes of soluble transport receptors, members of the importin-β protein …

[HTML][HTML] Dominant‐negative mutants of importin‐β block multiple pathways of import and export through the nuclear pore complex

U Kutay, E Izaurralde, FR Bischoff, IW Mattaj… - The EMBO …, 1997 - embopress.org
Nuclear protein import proceeds through the nuclear pore complex (NPC). Importin‐β
mediates translocation via direct interaction with NPC components and carries importin‐α …

Gradient of increasing affinity of importin β for nucleoporins along the pathway of nuclear import

I Ben-Efraim, L Gerace - The Journal of cell biology, 2001 - rupress.org
Nuclear import and export signals on macromolecules mediate directional, receptor-driven
transport through the nuclear pore complex (NPC) by a process that is suggested to involve …

Mechanisms of receptor‐mediated nuclear import and nuclear export

LF Pemberton, BM Paschal - Traffic, 2005 - Wiley Online Library
Nuclear transport of proteins and RNA occurs through the nuclear pore complex and is
mediated by a superfamily of transport receptors known collectively as karyopherins …

Importin β contains a COOH-terminal nucleoporin binding region important for nuclear transport

J Bednenko, G Cingolani, L Gerace - The Journal of cell biology, 2003 - rupress.org
Proteins containing a classical NLS are transported into the nucleus by the import receptor
importin β, which binds to cargoes via the adaptor importin α. The import complex is …

Transport pathways of macromolecules between the nucleus and the cytoplasm

SA Adam - Current opinion in cell biology, 1999 - Elsevier
Transport between the nucleus and cytoplasm involves both stationary components and
mobile factors acting in concert to move macromolecules through the nuclear pore complex …

Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase

M Seedorf, M Damelin, J Kahana… - Molecular and cellular …, 1999 - Am Soc Microbiol
Proteins to be transported into the nucleus are recognized by members of the importin-
karyopherin nuclear transport receptor family. After docking at the nuclear pore complex …

Exportin 7 defines a novel general nuclear export pathway

JM Mingot, MT Bohnsack, U Jäkle, D Görlich - The EMBO journal, 2004 - embopress.org
Most transport pathways between cell nucleus and cytoplasm are mediated by nuclear
transport receptors of the importin β family. These receptors are in continuous circulation …

[HTML][HTML] Nucleocytoplasmic transport: the soluble phase

IW Mattaj, L Englmeier - Annual review of biochemistry, 1998 - annualreviews.org
Active transport between the nucleus and cytoplasm involves primarily three classes of
macromolecules: substrates, adaptors, and receptors. Some transport substrates bind …