Human gene therapy and imaging in neurological diseases
AH Jacobs, A Winkler, MG Castro… - European journal of …, 2005 - Springer
Molecular imaging aims to assess non-invasively disease-specific biological and molecular
processes in animal models and humans in vivo. Apart from precise anatomical localisation …
processes in animal models and humans in vivo. Apart from precise anatomical localisation …
Seeing genes at work in the living brain with non-invasive molecular imaging
CM Deroose, V Reumers, Z Debyser… - Current gene …, 2009 - ingentaconnect.com
Over the past ten years, a variety of imaging techniques have been developed that allow
non-invasive detection of gene expression within the brain of intact mammals, ranging from …
non-invasive detection of gene expression within the brain of intact mammals, ranging from …
PET-based molecular imaging in neuroscience
AH Jacobs, H Li, A Winkeler, R Hilker, C Knoess… - European journal of …, 2003 - Springer
Positron emission tomography (PET) allows non-invasive assessment of physiological,
metabolic and molecular processes in humans and animals in vivo. Advances in detector …
metabolic and molecular processes in humans and animals in vivo. Advances in detector …
Positron emission tomography in neuroscience: An integrative part of clinical diagnostic methods and experimental research
B Schaller - Der Radiologe, 2005 - Springer
The role of molecular neuroimaging techniques is increasing in the understanding of
pathophysiological mechanism of diseases. To date, positron emission tomography is the …
pathophysiological mechanism of diseases. To date, positron emission tomography is the …
Molecular medicine successes in neuroscience
B Schaller, JF Cornelius, N Sandu - Molecular Medicine, 2008 - Springer
In this issue of Molecular Medicine, Irvine et al.(1) expound upon the application of
molecular biology in clinical medicine and the enabling of targeted interactions at a …
molecular biology in clinical medicine and the enabling of targeted interactions at a …
Role of in vivo imaging of the central nervous system for developing novel drugs
MA Rueger, LW Kracht, R Hilker… - The Quarterly Journal …, 2007 - search.proquest.com
Over the past decade imaging technologies employed in clinical neurosciences have
significantly advanced. Imaging is not only used for the diagnostic work-up of neurological …
significantly advanced. Imaging is not only used for the diagnostic work-up of neurological …
Molecular imaging of gliomas
AH Jacobs, C Dittmar, A Winkeler, G Garlip… - Molecular …, 2002 - journals.sagepub.com
Gliomas are the most common types of brain tumors. Although sophisticated regimens of
conventional therapies are being carried out to treat patients with gliomas, the disease …
conventional therapies are being carried out to treat patients with gliomas, the disease …
Neurodegenerative disease
DJ Doudet - Molecular Imaging and Biology, 2007 - Springer
These two words have become unwittingly popular in recent years. People from all strata of
society have started to recognize and worry about it at the same title as heart disease or …
society have started to recognize and worry about it at the same title as heart disease or …
Positron emission tomography and gene therapy: basic concepts and experimental approaches for in vivo gene expression imaging
I Peñuelas, JF Boán, JM Martı́-Climent, B Sangro… - Molecular Imaging & …, 2004 - Elsevier
More than two decades of intense research have allowed gene therapy to move from the
laboratory to the clinical setting, where its use for the treatment of human pathologies has …
laboratory to the clinical setting, where its use for the treatment of human pathologies has …
Molecular and functional imaging technology for the development of efficient treatment strategies for gliomas
AH Jacobs, A Winkeler, C Dittmar… - … in Cancer Research …, 2002 - journals.sagepub.com
Gliomas are the most common types of brain tumors, which invariably lead to death over
months or years. Before new and potentially more effective treatment strategies, such as …
months or years. Before new and potentially more effective treatment strategies, such as …