Oxidative stress is an unavoidable consequence of life in an oxygen-rich atmosphere.
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by …

The role of oxidative stress in causing liver diseases emerged in the early 1960s from the
laboratories of Trevor Slater, Mario Umberto Dianzani and others. These pioneering works …

Oxidative stress is a major pathogenetic event occurring in several liver disorders ranging
from metabolic to proliferative ones, and is a major cause of liver damage due to …

Oxidative stress and liver injury are strongly associated. Oxidative stress in the liver can be
triggered during different conditions and by specific etiologies, including hepatotoxins …

Oxygen is vital for life as it is required for many different enzymatic reactions involved in
intermediate metabolism and xenobiotic biotransformation. Moreover, oxygen consumption …

The liver, the bodies' largest solid internal organ, performs a substantial number of vital
metabolic functions and is the main organ for drug and xenobiotic metabolism. These …

The liver, the body's largest solid organ, performs a substantial number of vital metabolic
functions and is the main organ for drug and xenobiotic metabolism. These functions require …

Liver damage ranges from acute hepatitis to hepatocellular carcinoma, through apoptosis,
necrosis, inflammation, immune response, fibrosis, ischemia, altered gene expression and …

In humans, oxidative stress and antioxidant defenses are the sum of a complicated network
of enzymatic and non‐enzymatic processes. Depending on the stage and severity of …

Reactive oxygen species (ROS), a heterogeneous population of biologically active
intermediates, are generated as by-products of the aerobic metabolism and exhibit a dual …