A comparison of tibolone and conjugated equine estrogens effects on coronary artery atherosclerosis and bone density of postmenopausal monkeys

TB Clarkson, MS Anthony… - The Journal of Clinical …, 2001 - academic.oup.com
This study compared the effects of tibolone, a tissue-specific compound for the treatment of
climacteric symptoms and the prevention of osteoporosis, with those of conjugated equine …

A comparison of tibolone and hormone replacement therapy on coronary artery and myocardial function in ovariectomized atherosclerotic monkeys

JK Williams, J Hall, MS Anthony, TC Register… - Menopause, 2002 - journals.lww.com
Objective Tibolone is used to prevent osteoporosis and to treat climacteric symptoms. The
objectives of these studies were to measure and compare the effects of tibolone with …

Effects of tibolone on serum lipoprotein and apolipoprotein levels compared with a cyclical estrogen/progestogen regimen

E Farish, JF Barnes, CD Fletcher, K Ekevall… - Menopause, 1999 - journals.lww.com
Objective: The purpose of the study was to examine the effects of tibolone, a synthetic
steroid that alleviates climacteric symptoms and prevents bone loss without inducing …

Comparison of the antiatherosclerotic effect of tibolone with that of estradiol and ethinyl estradiol in cholesterol-fed, ovariectomized rabbits

P Zandberg, JLM Peters, PNM Demacker… - Menopause, 2001 - journals.lww.com
Objective Tibolone is a synthetic steroid with tissue-specific estrogenic, progestogenic, and
androgenic properties. The drug relieves climacteric symptoms and prevents osteoporosis …

Comparison of tibolone and conjugated equine estrogens effects on carotid artery atherosclerosis of postmenopausal monkeys

TB Clarkson, MS Anthony, TS Mikkola, RW St Clair - Stroke, 2002 - Am Heart Assoc
Background and Purpose—Tibolone is a tissue-specific compound that has favorable effects
on bone and menopausal symptoms without stimulating endometrium or breast, but lowers …

Effects of tibolone and conventional hormone replacement therapies on arterial and hepatic cholesterol accumulation and on circulating endothelin-1, vascular cell …

TC Register, JD Wagner, L Zhang, J Hall… - Menopause, 2002 - journals.lww.com
Objective Menopause and aging are associated with a marked increase in the incidence of
coronary heart disease as well as reductions in circulating estrogen, progestogen, and …

Serum cholesterol efflux potential in postmenopausal monkeys treated with tibolone or conjugated estrogens

TS Mikkola, MS Anthony… - Metabolism-Clinical …, 2002 - metabolismjournal.com
Tibolone is a synthetic steroid used for the treatment of climacteric symptoms and the
prevention of osteoporosis, but the effect on the cardiovascular system is unclear since …

Effects of tibolone and conjugated equine estrogens with or without medroxyprogesterone acetate on body composition and fasting carbohydrate measures in …

MK Shadoan, MS Anthony, SE Rankin, TB Clarkson… - Metabolism, 2003 - Elsevier
The effects of tibolone on body weight, body composition, and fasting carbohydrate
measures in surgically postmenopausal cynomolgus monkeys were compared to those of …

Comparative effects on bone mineral density of tibolone, transdermal estrogen and oral estrogen/progestogen therapy in postmenopausal women

GM Prelevic, C Bartram, J Wood, S Okolo… - Gynecological …, 1996 - Taylor & Francis
The aim of the study was to assess the comparative effects on bone mineral density (BMD)
in routine clinical practice of tibolone and estrogen (given either unopposed or combined …

A 3-year study of prevention of postmenopausal bone loss: conjugated equine estrogens plus medroxyprogesterone acetate versus tibolone

DTJM Bigler, S Renteria, T Pache, HJ Welti, M Landry… - …, 1998 - Taylor & Francis
The aim of this study was to investigate the effects of tibolone in the prevention of
postmenopausal bone loss over 3 years, and to compare these with the effects of sequential …