The most common laboratory abnormality in multiple sclerosis (MS) is an increased amount
of cerebrospinal fluid IgG and the presence of oligoclonal bands. Despite studies of the …

B cells are one of the key players in the pathogenesis of multiple sclerosis (MS). The
peripheral B cell distributions are similar in healthy persons and MS patients. In healthy …

Despite the current limited understanding of the etiology of multiple sclerosis (MS), genetic
susceptibility and environmental influences are known driving factors. MS is considered a T …

B cells are increasingly coming into play in the pathogenesis of multiple sclerosis (MS).
Here, we screened peripheral blood mononuclear cells (PBMC) from patients with clinically …

Multiple sclerosis (MS) is a multicomponent disease that is marked by continual
inflammation, demyelination and irreparable damage to the central nervous system. While it …

The role B cells and humoral immunity play in multiple sclerosis (MS) is continually evolving.
Recent discoveries include advances in lesion classification, identification of B cell clonal …

Understanding the pathogenesis of complex immunologic disorders such as multiple
sclerosis (MS) is challenging. Abnormalities in many different cell types are observed in the …

Over the past two decades B cells have increasingly moved into the spotlight in multiple
sclerosis (MS) research. This interest was fuelled by growing understanding and acceptance …

Interest in the role of B-cells in multiple sclerosis (MS) pathogenesis has increased, and a
number of B-cell targeted therapies are currently in clinical trials. B-cells are key mediators …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). The mainstream view is that MS is caused by an autoimmune attack …