Key points• The molecular basis of left–right asymmetries in brain structure and function is a
central question in neuroscience.• We have previously demonstrated that the neuronal …

The role of the MHC class II transactivator (CIITA) in Ag presentation by astrocytes and
susceptibility to experimental autoimmune encephalomyelitis (EAE) was examined using …

Mechanisms of major histocompatibility complex (MHC) class I gene regulation in cells of
the CNS have been studied in vitro. Astrocytes in primary cultures, but neither …

The regulation of major histocompatibility complex (MHC) class I, interferon (IFN)-β, and anti-
viral state expression in neurons was analyzed. Treatment of neurons with either double …

The expression of class I and class II histocompatibility antigens by myelin basic protein
(MBP)-positive oligodendrocytes, in response to exogenous cytokines, has been …

Major histocompatibility complex class I (MHCI) proteins have been implicated in neuronal
function through the modulation of neuritogenesis, synaptogenesis, synaptic plasticity and …

Studies have demonstrated neuronal expression of class I major histocompatibility complex
(MHC) mRNA and protein in normal and developing brain and in response to injury or viral …

An axon lesion to a bulbar or spinal motoneuron is followed by a typical retrograde response
at the cell body level, including the removal or 'stripping'of synapses from the perikaryon and …

Proteins of the major histocompatibility complex class I (MHC I), predominantly known for
antigen presentation in the immune system, have recently been shown to be necessary for …

MHC class I proteins are cell-surface ligands that bind to T cell receptors and other
immunoreceptors and act to regulate the activation state of immune cells. Recent work has …