The cells of the central nervous system (CNS) have the peculiarity of physiologically
expressing very low levels of HLA molecules. In multiple sclerosis (MS), however, as in …

The brain has long been considered to be an immunologically privileged site. However,
privilege is not absolute, as has been shown by the inability of foreign tissue grafts to survive …

An increasing number of studies support an unexpected role for immune molecules in
regulating healthy brain functions during development and in adulthood. Here we review the …

There are more than 50 class I MHC (MHCI) molecules in the mouse genome, some of
which are now known to be expressed in neurons; however, the role of classical MHCI …

Recent evidence that astrocytes can be induced to express the class II major
histocompatability (MHC) antigens suggests that these cells may be involved in the …

Whether neurons express major histocompatibility complex (MHC) class I genes has not
been firmly established. The techniques of confocal laser microscopy, patch clamp …

Presentation of antigen is key to the development of the immune response, mediated by
association of antigen with major histocompatibility complex glycoproteins abbreviated as …

HLA-G is a non-classical major histocompatibility complex (MHC) class I antigen with highly
limited tissue distribution under non-pathological conditions. Although capable of acting as a …

There are numerous observations reporting that phagocytes expressing major
histocompatibility complex (MHC) Class II molecules are associated with the central nervous …

Murine retinal glia are normally negative for major histocompatibility complex (MHC) Class II
antigens and express low levels of MHC Class I and intercellular adhesion molecule-1 …