Mechanistic links between obesity, insulin, and cancer
RJ Perry, GI Shulman - Trends in cancer, 2020 - cell.com
Obesity and type 2 diabetes (T2D) increase the prevalence and worsen the prognosis of
more than a dozen tumor types; however, the mechanism for this association remains hotly …
more than a dozen tumor types; however, the mechanism for this association remains hotly …
Obesity, type 2 diabetes, and cancer risk
T Scully, A Ettela, D LeRoith, EJ Gallagher - Frontiers in oncology, 2021 - frontiersin.org
Obesity and type 2 diabetes have both been associated with increased cancer risk and are
becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and …
becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and …
Obesity and cancer, a case for insulin signaling
Y Poloz, V Stambolic - Cell death & disease, 2015 - nature.com
Obesity is a worldwide epidemic, with the number of overweight and obese individuals
climbing from just over 500 million in 2008 to 1.9 billion in 2014. Type 2 diabetes (T2D) …
climbing from just over 500 million in 2008 to 1.9 billion in 2014. Type 2 diabetes (T2D) …
Insulin and cancer: a tangled web
BP Leitner, S Siebel, ND Akingbesote… - Biochemical …, 2022 - portlandpress.com
For a century, since the pioneering work of Otto Warburg, the interwoven relationship
between metabolism and cancer has been appreciated. More recently, with obesity rates …
between metabolism and cancer has been appreciated. More recently, with obesity rates …
[HTML][HTML] Obesity, diabetes, and increased cancer progression
DS Kim, PE Scherer - Diabetes & metabolism journal, 2021 - synapse.koreamed.org
Rates of obesity and diabetes have increased significantly over the past decades and the
prevalence is expected to continue to rise further in the coming years. Many observations …
prevalence is expected to continue to rise further in the coming years. Many observations …
Obesity, type 2 diabetes, and cancer: the insulin and IGF connection
DH Cohen, D LeRoith - Endocrine-related cancer, 2012 - erc.bioscientifica.com
Epidemiological studies suggest a positive association between obesity and type 2 diabetes
mellitus (T2D) with the risk of cancer and cancer-related mortality. Insulin resistance …
mellitus (T2D) with the risk of cancer and cancer-related mortality. Insulin resistance …
Obesity and diabetes: the increased risk of cancer and cancer-related mortality
EJ Gallagher, D LeRoith - Physiological reviews, 2015 - journals.physiology.org
Obesity and type 2 diabetes are becoming increasingly prevalent worldwide, and both are
associated with an increased incidence and mortality from many cancers. The metabolic …
associated with an increased incidence and mortality from many cancers. The metabolic …
Obesity, type-2 diabetes and cancer: mechanistic insights
K Kashfi, CL Rosen, M Aslan - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Obesity leads to many diseases including hypercholesterolemia, type-2 diabetes,
hypertension, cardiovascular disease, and cancer. It is the fastest-growing lethal disease in …
hypertension, cardiovascular disease, and cancer. It is the fastest-growing lethal disease in …
The links between insulin resistance, diabetes, and cancer
E Orgel, SD Mittelman - Current diabetes reports, 2013 - Springer
The growing epidemic of obesity has resulted in a large increase in multiple related
diseases. Recent evidence has strengthened the proposed synergistic relationship between …
diseases. Recent evidence has strengthened the proposed synergistic relationship between …
The pathway from diabetes and obesity to cancer, on the route to targeted therapy
EJ Gallagher, Y Fierz, RD Ferguson, D LeRoith - Endocrine Practice, 2010 - Elsevier
Objective To review the epidemiologic studies that describe the relationships among
diabetes, obesity, and cancer; animal studies that have helped to decipher the mechanisms …
diabetes, obesity, and cancer; animal studies that have helped to decipher the mechanisms …