[HTML][HTML] Clinical proteomics: current status, challenges, and future perspectives

SH Chiou, CY Wu - The Kaohsiung journal of medical sciences, 2011 - Elsevier
This account will give an overview and evaluation of the current advances in mass
spectrometry (MS)-based proteomics platforms and technology. A general review of some …

Mass spectrometry-based proteomics in biomedical research: emerging technologies and future strategies

GM Walsh, JC Rogalski, C Klockenbusch… - Expert reviews in …, 2010 - cambridge.org
In recent years, the technology and methods widely available for mass spectrometry (MS)-
based proteomics have increased in power and potential, allowing the study of protein-level …

Mass spectrometry-based clinical proteomics profiling: current status and future directions

P Findeisen, M Neumaier - Expert Review of Proteomics, 2009 - Taylor & Francis
Biomarker discovery and validation is a central application in current proteomic research to
improve the diagnosis, treatment monitoring and prognosis of many diseases, including …

Global and targeted quantitative proteomics for biomarker discovery

TD Veenstra - Journal of Chromatography B, 2007 - Elsevier
The extraordinary developments made in proteomic technologies in the past decade have
enabled investigators to consider designing studies to search for diagnostic and therapeutic …

[PDF][PDF] SnapShot: clinical proteomics

Y Zhu, R Aebersold, M Mann, T Guo - Cell, 2021 - cell.com
In-depth quantitative proteomic analysis of clinical specimens offers unique and invaluable
insights into their protein composition and biochemical state in physiological and …

Recent advances in clinical proteomics using mass spectrometry

P Dowling, P Meleady, M Henry, M Clynes - Bioanalysis, 2010 - Taylor & Francis
The ultimate objective of clinical proteomics is the successful discovery, validation and
translation of biomarkers, together with new therapeutic targets into medical practices. New …

Mass spectrometry-based clinical proteomics

W Pusch, MT Flocco, SM Leung, H Thiele… - …, 2003 - Taylor & Francis
In recent years, mass spectrometry (MS) has been recognized as a 'Gold Standard'tool for
the identification and analysis of individual proteins in expression proteomics studies …

Mass spectrometry in clinical proteomics–from the present to the future

M Palmblad, A Tiss, R Cramer - PROTEOMICS–Clinical …, 2009 - Wiley Online Library
MS is an important analytical tool in clinical proteomics, primarily in the disease‐specific
discovery, identification and characterisation of proteomic biomarkers and patterns. MS …

Methods and approaches for the comprehensive characterization and quantification of cellular proteomes using mass spectrometry

SP Mirza, M Olivier - Physiological genomics, 2008 - journals.physiology.org
Proteomics has been proposed as one of the key technologies in the postgenomic era. So
far, however, the comprehensive analysis of cellular proteomes has been a challenge …

Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

AG Birhanu - Clinical Proteomics, 2023 - Springer
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …