Fundamentals of bicarbonate secretion in epithelia

I Novak, J Praetorius - Basic Epithelial Ion Transport Principles and …, 2020 - Springer
Certain epithelia secrete HCO 3− to drive fluid secretion, to modify luminal pH and
properties of secreted mucus, and to fulfill other functions of a given epithelium …

Fundamentals of bicarbonate secretion in epithelia

I Novak, J Praetorius - Ion channels and transporters of epithelia in health …, 2016 - Springer
Certain epithelia secrete HCO 3− to buffer luminal fluids and protect cells against acids.
Dysregulation of HCO 3− secretion can lead to conditions such as malabsorption, acid/base …

Bicarbonate secretion and acid/base sensing by the intestine

HM Becker, UE Seidler - Pflügers Archiv-European Journal of Physiology, 2024 - Springer
The transport of bicarbonate across the enterocyte cell membrane regulates the intracellular
as well as the luminal pH and is an essential part of directional fluid movement in the gut …

Na+-coupled bicarbonate transporters in duodenum, collecting ducts and choroid plexus.

J Praetorius - Journal of nephrology, 2010 - europepmc.org
Epithelia cover the internal and external surfaces of the organism and form barriers between
the various compartments. Some of these epithelia are specialized for effective …

A double-membrane model for urinary bicarbonate secretion

DL Stetson, R Beauwens… - American Journal …, 1985 - journals.physiology.org
To define the transport pathway for HCO-3 secretion (JHCO3) across the apical and
basolateral membranes of turtle bladder, we examined the effects of cAMP …

Role of calcium signaling in epithelial bicarbonate secretion

J Jung, MG Lee - Cell Calcium, 2014 - Elsevier
Transepithelial bicarbonate secretion plays a key role in the maintenance of fluid and
protein secretion from epithelial cells and the protection of the epithelial cell surface from …

Why bicarbonate?

JR Casey - Biochemistry and cell biology, 2006 - cdnsciencepub.com
Bicarbonate is a simple single carbon molecule that plays surprisingly important roles in
diverse biological processes. Among these are photosynthesis, the Krebs cycle, whole-body …

Bicarbonate permeation through anion channels: its role in health and disease

DH Shin, M Kim, Y Kim, I Jun, J Jung, JH Nam… - … -European Journal of …, 2020 - Springer
Many anion channels, frequently referred as Cl− channels, are permeable to different anions
in addition to Cl−. As the second-most abundant anion in the human body, HCO 3 …

Bicarbonate transport in cell physiology and disease

E Cordat, JR Casey - Biochemical Journal, 2009 - portlandpress.com
The family of mammalian bicarbonate transport proteins are involved in a wide-range of
physiological processes. The importance of bicarbonate transport follows from the …

[HTML][HTML] Hepatobiliary acid-base homeostasis: Insights from analogous secretory epithelia

DC Trampert, SFJ van de Graaf, A Jongejan… - Journal of …, 2021 - Elsevier
Many epithelia secrete bicarbonate-rich fluid to generate flow, alter viscosity, control pH and
potentially protect luminal and intracellular structures from chemical stress. Bicarbonate is a …