The castration-induced regression and testosterone stimulated regrowth of the vasculature
in the rat ventral prostate lobe were studied using stereological techniques. Seven days after …

BACKGROUND Androgenic steroids regulate the development and size of the mammalian
prostate gland. The mechanism (s) for this growth control might involve a direct effect on …

Recent studies have found that blood flow to the rat ventral prostate gland is drastically
reduced at an early time after castration. These observations caused us to reevaluate the …

There is now considerable direct evidence that tumor growth is angiogenesis dependent,
and that tumor mass is under the tight control of microvascular endothelium (1). New …

AIMS: Testosterone is beneficial to the cardiovascular system due to its direct coronary
vasodilatory action and its circulatory deficiency is associated with coronary artery disease …

PURPOSE: Previous studies demonstrating a rapid and drastic reduction of blood flow to the
rat prostate gland resulting from castration caused us to consider the influence of castration …

PURPOSE: Recent studies suggest that the vasculature is important for the control of
prostate growth. Castration induces an involution of the prostate gland and its vasculature …

The response of the prostate tissue microenvironment to androgen deprivation (AD)
represents a critical component in the treatment of benign prostatic hyperplasia and prostate …

BACKGROUND Castration‐induced involution of the normal prostate is caused by primary
effects in the prostate stroma and vasculature, but if this is the case also in tumors is …

Aim To investigate the effect of androgen on the proliferation, differentiation and regression
of canine prostatic stromal cells in vivo and human stromal cells in vitro. Methods Twenty …