Recent progress in biological activities of indole and indole alkaloids
The indole scaffold is found in a wide range of bioactive heterocycles and natural products.
Moreover, the indole moiety is considered as the active principle in several alkaloids such …
Moreover, the indole moiety is considered as the active principle in several alkaloids such …
Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view
N Chadha, O Silakari - European Journal of Medicinal Chemistry, 2017 - Elsevier
Indoles constitute extensively explored heterocyclic ring systems with wide range of
applications in pathophysiological conditions that is, cancer, microbial and viral infections …
applications in pathophysiological conditions that is, cancer, microbial and viral infections …
The Multi‐Pharmacological Targeted Role of Indole and its Derivatives: A review
B Suliphuldevara Mathada… - …, 2023 - Wiley Online Library
Heterocycles are a privileged motif that appears as a momentous objective in medicinal
chemistry. An important class of compounds for drug discovery and design is indole and its …
chemistry. An important class of compounds for drug discovery and design is indole and its …
Medicinal perspective of indole derivatives: recent developments and structure-activity relationship studies
Heterocyclic compounds play a significant role in various biological processes of the human
body and many of them are in clinical use due to their diverse, chemical and biological …
body and many of them are in clinical use due to their diverse, chemical and biological …
Indoles—A promising scaffold for drug development
TV Sravanthi, SL Manju - European Journal of Pharmaceutical Sciences, 2016 - Elsevier
Generally, heterocycles occupy a prominent place in chemistry due to their wide range of
applications in the fields of drug design, photochemistry, agrochemicals, dyes and so on …
applications in the fields of drug design, photochemistry, agrochemicals, dyes and so on …
Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives
A Kumari, RK Singh - Bioorganic chemistry, 2019 - Elsevier
Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …
compound with wide ranges of pharmacological activities due to different mechanisms of …
[HTML][HTML] Synthesis of indole derivatives as prevalent moieties present in selected alkaloids
MM Heravi, Z Amiri, K Kafshdarzadeh, V Zadsirjan - RSC advances, 2021 - pubs.rsc.org
Indoles are a significant heterocyclic system in natural products and drugs. They are
important types of molecules and natural products and play a main role in cell biology. The …
important types of molecules and natural products and play a main role in cell biology. The …
An insight into the medicinal perspective of synthetic analogs of indole: A review
PV Thanikachalam, RK Maurya, V Garg… - European journal of …, 2019 - Elsevier
Heterocycles occupy a salient place in chemistry due to their wide range of activity in the
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …
[HTML][HTML] Plant-based indole alkaloids: A comprehensive overview from a pharmacological perspective
F Omar, AM Tareq, AM Alqahtani, K Dhama… - Molecules, 2021 - mdpi.com
Plant-based indole alkaloids are very rich in pharmacological activities, and the indole
nucleus is considered to contribute greatly to these activities. This review's fundamental …
nucleus is considered to contribute greatly to these activities. This review's fundamental …
From nature to drug discovery: the indole scaffold as a 'privileged structure'
FR de Sa Alves, EJ Barreiro… - Mini reviews in …, 2009 - ingentaconnect.com
The indole scaffold probably represents one of the most important structural subunits for the
discovery of new drug candidates. The demonstration that many alkaloids contain the indole …
discovery of new drug candidates. The demonstration that many alkaloids contain the indole …