Biomarkers in amyotrophic lateral sclerosis: current status and future prospects

R McMackin, P Bede, C Ingre, A Malaspina… - Nature Reviews …, 2023 - nature.com
Disease heterogeneity in amyotrophic lateral sclerosis poses a substantial challenge in drug
development. Categorization based on clinical features alone can help us predict the …

Biomarkers in amyotrophic lateral sclerosis: A review of new developments

N Verber, PJ Shaw - Current Opinion in Neurology, 2020 - journals.lww.com
Biomarkers in amyotrophic lateral sclerosis: a review of new... : Current Opinion in
Neurology Biomarkers in amyotrophic lateral sclerosis: a review of new developments …

Biomarkers for amyotrophic lateral sclerosis

S Witzel, K Mayer, P Oeckl - Current Opinion in Neurology, 2022 - journals.lww.com
Biomarkers for amyotrophic lateral sclerosis : Current Opinion in Neurology Biomarkers for
amyotrophic lateral sclerosis : Current Opinion in Neurology Log in or Register Subscribe to …

Ensuring continued progress in biomarkers for amyotrophic lateral sclerosis

MR Turner, M Benatar - Muscle & nerve, 2015 - Wiley Online Library
Multiple candidate biomarkers for amyotrophic lateral sclerosis (ALS) have emerged across
a range of platforms. Replication of results, however, has been absent in all but a few cases …

Emerging molecular biomarker targets for amyotrophic lateral sclerosis

J Costa, M de Carvalho - Clinica chimica acta, 2016 - Elsevier
Amyotrophic lateral sclerosis is a rapidly progressive neurodegenerative disease that affects
upper (UMN) and lower motor (LMN) neurons. It is associated with a short survival and there …

Blood biomarkers for amyotrophic lateral sclerosis: myth or reality?

L Robelin… - BioMed research …, 2014 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a fatal condition primarily characterized by the
selective loss of upper and lower motor neurons. At present, the diagnosis and monitoring of …

Neurophysiological biomarkers in amyotrophic lateral sclerosis

S Vucic, SB Rutkove - Current opinion in neurology, 2018 - journals.lww.com
Neurophysiological biomarkers in amyotrophic lateral scleros... : Current Opinion in
Neurology Neurophysiological biomarkers in amyotrophic lateral sclerosis : Current Opinion …

Cerebrospinal fluid biomarkers of disease activity and progression in amyotrophic lateral sclerosis

M Dreger, R Steinbach, M Otto, MR Turner… - Journal of Neurology …, 2022 - jnnp.bmj.com
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative disease,
and only modest disease-modifying strategies have been established to date. Numerous …

Biomarkers in amyotrophic lateral sclerosis

MR Turner, MC Kiernan, PN Leigh, K Talbot - The Lancet Neurology, 2009 - thelancet.com
Amyotrophic lateral sclerosis (ALS; motor neuron disease) is a relentlessly progressive
disorder. After half a century of trials, only one drug with modest disease-modifying potency …

Multicentre quality control evaluation of different biomarker candidates for amyotrophic lateral sclerosis

S Lehnert, J Costa, M De Carvalho, J Kirby… - … lateral sclerosis and …, 2014 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that mainly
causes degeneration of the upper and lower motor neurons, ultimately leading to paralysis …