Purpose: No study has yet analyzed whether changes in relative expression levels of
progesterone receptor (PR) isoforms A and B in human breast tumors have significance in …

Progesterone receptors (PRs) are prognostic markers in breast cancers irrespective of the
patient's progestational status. However, there are two PR isoforms, PR-A and PR-B, that are …

The human progesterone receptor (PR) is a ligand-activated nuclear transcription factor that
mediates progesterone action in target tissues. Two PR proteins, PR-A (M r 81,000–83,000) …

Even the first expression profiling studies of breast cancers have generated new insights.
They suggest for example, that information about tumor aggressiveness, prognosis …

In the present study, we used Western blot analysis to determine the expression of the
progesterone receptor (PR) isoforms, PR-B and PR-A, in breast tumors (n= 53), and …

The receptor for the female hormone progesterone (PR), like that for estrogen (ER), is an
important predictive marker for response to endocrine therapy in patients with breast cancer …

The human progesterone receptor (PR) is a ligand-activated nuclear transcription factor
which mediates progesterone action in target tissues. Two PR proteins, PR A (81–83 kDa) …

Sixty to seventy percent of all primary human breast cancers are estrogen-dependent and
express both estrogen (ER) and progesterone receptors (PR). Whereas expression of the …

The PR-A and PR-B isoforms of progesterone receptors (PR) have different physiological
functions, and their ratio varies widely in breast cancers. To determine whether the two PR …

Background Patient prognosis and response to endocrine therapy in breast cancer correlate
with protein expression of both estrogen receptor (ER) and progesterone receptor (PR), with …