The term allergy was coined in 1906 by the Austrian scientist and pediatrician Clemens
Freiherr von Pirquet. In 1976, Dietrich Kraft became the head of the Allergy and Immunology …

Abstract In Northern America and Europe a great number of people are suffering from birch
pollen allergy and pollen related food allergies. The trigger for these immunological …

Birch pollen allergy is highly prevalent, with up to 100 million reported cases worldwide.
Proteases in such allergen sources have been suggested to contribute to primary …

Nitration of the major birch pollen allergen Bet v 1 alters the immune responses toward this
protein, but the underlying chemical mechanisms are not yet understood. Here we address …

Allergy prevalence has increased in industrialized countries. One contributing factor could
be pollution, which can cause nitration of allergens exogenously (in the air) or …

Allergens are substances that cause abnormal immune responses and can originate from
various sources. IgE-mediated allergies are one of the most common and severe types of …

Bet v 1 is the major birch pollen allergen and therefore the main cause of type I allergies
observed in early spring. It is composed of 159 amino acid residues adding up to a …

Worldwide, more than 1 billion people suffer from allergic diseases. However, until now it is
not fully understood how certain proteins can induce allergic immune responses, while …

Pollen of the European and Asian white birch (Betula pendula and B. platyphylla) causes
hay fever in humans. The allergenic potency of other birch species is largely unknown. To …