Differences in the intrinsic immunogenicity and allergenicity of B et v 1 and related food allergens revealed by site‐directed mutagenesis
Background Birch pollen allergies are frequently associated with adverse reactions to
various fruits, nuts, or vegetables, described as pollen–food syndrome (PFS) and caused by …
various fruits, nuts, or vegetables, described as pollen–food syndrome (PFS) and caused by …
Comparative proteomics of common allergenic tree pollens of birch, alder, and hazel
B Darnhofer, T Tomin, L Liesinger, M Schittmayer… - Allergy, 2021 - Wiley Online Library
Background In addition to known allergens, other proteins in pollen can aid the development
of an immune response in allergic individuals. The contribution of the “unknown” protein …
of an immune response in allergic individuals. The contribution of the “unknown” protein …
The allergen Mus m 1.0102: Dissecting the relationship between molecular conformation and allergenic potency
E Ferrari, E Casali, SE Burastero, A Spisni… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Abstract Background The species Mus musculus experiences an obligate proteinuria:
predominant are the Major Urinary Proteins (MUPs), that, collectively known as the major …
predominant are the Major Urinary Proteins (MUPs), that, collectively known as the major …
Structural glycobiology of the major allergen of Artemisia vulgaris pollen, Art v 1: O-glycosylation influence on the protein dynamics and allergenicity
L Pol-Fachin, H Verli - Glycobiology, 2012 - academic.oup.com
Abstract Art v 1 is the major allergen of mugwort (Artemisia vulgaris) pollen. It is formed by
an N-terminal globular defensin-like part and a C-terminal proline-rich domain. As the …
an N-terminal globular defensin-like part and a C-terminal proline-rich domain. As the …
Reshaping the Bet v 1 fold modulates TH polarization
BACKGROUND: Several alternative mechanisms have been proposed to explain why some
proteins are able to induce a TH2-biased and IgE-mediated immune response. These …
proteins are able to induce a TH2-biased and IgE-mediated immune response. These …
Influence of Hydrophobic Cargo Binding on the Structure, Stability, and Allergenicity of the Cockroach Allergen Bla g 1
AC Foo, PM Thompson, S Arora, EF DeRose… - Journal of Allergy and …, 2019 - jacionline.org
Methods The effect of various fatty-acid, phospholipid, and lipotechchoic acid (LTA) cargoes
on Bla g 1 structure and thermostability was assessed using circular dichroism coupled with …
on Bla g 1 structure and thermostability was assessed using circular dichroism coupled with …
[图书][B] Stability of the Bet v 1 cross-reactive allergens Api g 1 and Dau c 1: a biophysical approach
MA Bollen - 2009 - search.proquest.com
The allergen Bet v 1 is known as the primary sensitizer for birch pollen-related food allergy
and is responsible for IgE cross-reactivity to pathogenesis-related 10 (PR-10) proteins from …
and is responsible for IgE cross-reactivity to pathogenesis-related 10 (PR-10) proteins from …
Antigen aggregation decides the fate of the allergic immune response
N Zaborsky, M Brunner, M Wallner, M Himly… - The journal of …, 2010 - journals.aai.org
Previously, defined naturally occurring isoforms of allergenic proteins were classified as
hypoallergens and therefore suggested as an agent for immunotherapy in the future. In this …
hypoallergens and therefore suggested as an agent for immunotherapy in the future. In this …
A hypoallergenic variant of the major birch pollen allergen shows distinct characteristics in antigen processing and T‐cell activation
C Kitzmüller, M Wallner, S Deifl, S Mutschlechner… - Allergy, 2012 - Wiley Online Library
Background BM 4 is a novel genetically engineered variant of the major birch pollen
allergen B et v 1 that lacks the typical B et v 1‐like fold and displays negligible I g E‐binding …
allergen B et v 1 that lacks the typical B et v 1‐like fold and displays negligible I g E‐binding …
Crystallization and preliminary x‐ray investigation at 2.0 Å resolution of Bet v 1, a birch pollen protein causing IgE‐mediated allergy
MD Spangfort, JN Larsen… - … : Structure, Function, and …, 1996 - Wiley Online Library
The 17 kDa protein from Betula verrucosa (White Birch) pollen, Bet v 1, is the clinically most
important birch pollen allergen causing immediate Type I IgE‐mediated allergy. The three …
important birch pollen allergen causing immediate Type I IgE‐mediated allergy. The three …