Quantitative guidelines to distinguish allergenic proteins from related, but non-allergenic
ones are urgently needed for regulatory agencies, biotech companies and physicians. In a …

Bet v 1, the major allergen of birch pollen, displays a considerable degree of heterogeneity.
Several charge variants have been detected by two-dimensional IgE immunoblots and …

Cuticle-degrading serine protease Ver112, which derived from a nematophagous fungus
Lecanicillium psalliotae, has been exhibited to have high cuticle-degrading and nematicidal …

Background Birch pollen allergy represents the main cause of winter and spring pollinosis in
the temperate climate zone of the northern hemisphere and sensitization towards Bet v 1 …

Hyperstable miniproteins can be de novo designed to tightly bind protein targets, a
promising new avenue for treating infectious disease. Pioneering work by Chevalier et …

This thesis explores a wide array of topics related to the protein folding problem, ranging
from the folding mechanism, ab initio structure prediction and protein design, to the …

In more than 20% of the world population, sensitization to house dust mite allergens triggers
typical allergic diseases such as allergic rhinitis and asthma. Amongst the 23 mite allergen …

A high percentage of birch pollen allergic patients also experience food hypersensitivity
which results from common epitopes on the corresponding allergens. In order to analyze …

The major birch pollen allergen Bet v 1 is the main elicitor of airborne type I allergies and
belongs to the family 10 of pathogenesis related proteins. Bet v 1 is the most extensively …

BACKGROUND: Bet v 1 family is a large group of allergens present in pollen and plant-
derived foods. They show similarity in sequence and 3D structure, properties often …