Lipoprotein (a)(Lp (a)) is a risk factor for cardiovascular diseases and mainly regulated by
the complex LPA gene. We investigated the types of variation in the LPA gene and their …

Lipoprotein (a)[Lp (a)] concentrations are among the strongest genetic risk factors for
cardiovascular disease and present pronounced interethnic and interindividual differences …

Background and aims High lipoprotein (a)[Lp (a)] concentrations are associated with
increased coronary artery disease (CAD) risk. Lp (a) is regulated mainly genetically by the …

Background—Functional copy number variation in the apolipoprotein (a) gene (LPA)
underlies a variable number of protein kringle domains repeated in tandem in the lipoprotein …

Background The concentrations of the highly atherogenic lipoprotein (a)[Lp (a)] are mainly
genetically determined by the LPA gene locus. However, up to 70% of the coding sequence …

Abstract Background Lipoprotein (a)(Lp (a)) concentrations are a major independent risk
factor for coronary artery disease (CAD) and are mainly determined by variation in LPA. Up …

Recent advances in drug development aim to transi-tion lipoprotein (a)(Lp [a]) from a
predictive biomarker of cardiovascular disease to a therapeutic target. Among those with …

Abstract Background Lipoprotein (a)[Lp (a)] level variability, related to atherothrombotic risk
increase, is mainly attributed to LPA gene, encoding apolipoprotein (a), with kringle IV type 2 …

Abstract Lipoprotein (a)[Lp (a)] is an independent risk factor for atherosclerosis-related
events that is under strong genetic control (heritability= 0.68–0.98). However, causal …

Abstract Background Lipoprotein (a)[Lp (a)], which is genetically determined by the LPA
gene kringle IV type 2 (KIV-2) repeat copy number, has previously been reported in different …