An effective approach by a chelate reaction in optimizing the setting process of strontium‐incorporated calcium phosphate bone cement

GM Kuang, WP Yau, WM Lam, J Wu… - … Research Part B …, 2012 - Wiley Online Library
Strontium (Sr) plays a special role in enhancing the biological osteo‐stimulation of calcium
phosphate cement (CPC), not only increasing osteoblast‐related gene expression and the …

A novel and easy-to-prepare strontium (II) modified calcium phosphate bone cement with enhanced mechanical properties

M Schumacher, A Henß, M Rohnke, M Gelinsky - Acta biomaterialia, 2013 - Elsevier
The aim of this study was to evaluate two different approaches to obtaining strontium-
modified calcium phosphate bone cements (SrCPCs) without elaborate synthesis of Sr …

A novel strontium (II)-modified calcium phosphate bone cement stimulates human-bone-marrow-derived mesenchymal stem cell proliferation and osteogenic …

M Schumacher, A Lode, A Helth, M Gelinsky - Acta biomaterialia, 2013 - Elsevier
In the present study, the in vitro effects of novel strontium-modified calcium phosphate bone
cements (SrCPCs), prepared using two different approaches on human-bone-marrow …

Strontium exerts dual effects on calcium phosphate cement: Accelerating the degradation and enhancing the osteoconductivity both in vitro and in vivo

GM Kuang, WP Yau, J Wu, KWK Yeung… - … Research Part A, 2015 - Wiley Online Library
Calcium phosphate cements (CPCs) have long been used as osteoconductive bone
substitutes in the treatment of bone defects. However, the degradation rate of CPC is …

[HTML][HTML] In vitro and in vivo evaluation of injectable strontium-modified calcium phosphate cement for bone defect repair in rats

H Xu, L Zhu, F Tian, C Wang, W Wu, B Lu… - International Journal of …, 2022 - mdpi.com
Calcium phosphate cement (CPC) has been widely studied, but its lack of osteoinductivity
and inadequate mechanical properties limit its application, while strontium is able to …

Strontium substitution in apatitic CaP cements effectively attenuates osteoclastic resorption but does not inhibit osteoclastogenesis

M Schumacher, AS Wagner, J Kokesch-Himmelreich… - Acta biomaterialia, 2016 - Elsevier
Strontium ions were discovered to exert a dual effect on bone turnover, namely an inhibition
of cell-driven bone resorption and a simultaneous stimulation of new bone tissue formation …

Preparation and characterization of a novel strontium-containing calcium phosphate cement with the two-step hydration process

T Yu, J Ye, Y Wang - Acta Biomaterialia, 2009 - Elsevier
A novel Sr-containing calcium phosphate cement (CPC) with excellent compressive
strength, good radiopacity and a suitable setting time was developed in this work. The two …

Setting properties and in vitro bioactivity of strontium‐enriched gelatin–calcium phosphate bone cements

S Panzavolta, P Torricelli, L Sturba… - … Research Part A: An …, 2008 - Wiley Online Library
Strontium is known to reduce bone resorption and stimulate bone formation. We have
investigated the effect of strontium on the setting properties and in vitro bioactivity of a …

[HTML][HTML] A novel fast-setting strontium-containing hydroxyapatite bone cement with a simple binary powder system

L Sun, T Li, S Yu, M Mao, D Guo - Frontiers in Bioengineering and …, 2021 - frontiersin.org
In recent years, strontium-substituted calcium phosphate bone cement (Sr-CPC) has
attracted more and more attentions in the field of bone tissue repair due to its …

[HTML][HTML] Substitutions of strontium in bioactive calcium silicate bone cements stimulate osteogenic differentiation in human mesenchymal stem cells

TH Huang, CT Kao, YF Shen, YT Lin, YT Liu… - Journal of Materials …, 2019 - Springer
Calcium silicate cements have been considered as alternative bone substitutes owing to its
extraordinary bioactivity and osteogenicity. Unfortunately, the major disadvantage of the …