Background Recent evidence shows that inducing ferroptosis may improve efficacy of tumor
therapy. However, ferroptosis-related genes have been little studied in patients with breast …

Ferroptosis is an iron-dependent, non-apoptotic form of cell death involving in various
disease processes. Mechanistically, glutathione peroxidase 4 (GPX4) which belongs to the …

Increasing evidence supports that ferroptosis plays an important role in tumor growth
inhibition. Sorafenib, originally identified as an inhibitor of multiple oncogenic kinases, has …

As a main subtype of lung cancer, the current situation of non-small cell lung cancer
(NSCLC) remains severe worldwide with a 19% survival rate at 5 years. As the conventional …

Ferroptosis has become a topic of rapidly growing interest in recent years, and has possible
therapy implications in cancer therapy. Although excessive autophagy may contribute to …

The activation of ferroptosis is a new effective way to treat drug-resistant solid tumors.
Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid …

Ferroptosis is a form of programmed cell death characterized by intracellular iron
accumulation and lipid peroxidation, and earlier studies identified glutathione peroxidase 4 …

Metformin is a widely prescribed hypoglycemic drug. Many studies have shown its anti-
cancer properties. In the present study, we aimed to explore the effect of metformin on breast …

Ferroptosis is emerging as a new form of regulated cell death driven by oxidative injury
promoting lipid peroxidation in an iron-dependent manner. High mobility group box 1 …

Glioblastoma, the most aggressive form of malignant glioma, is very difficult to treat because
of its aggressively invasive nature and high recurrence rates. RAS‐selective lethal 3 (RSL3) …