Antisense repression was used as a method to alter gene function in the human-pathogenic
fungus Cryptococcus neoformans. The calcineurin A gene (CNA1) and the laccase gene …

Cryptococcus neoformans is an opportunistic fungal pathogen that primarily affects
immunocompromised individuals. Reverse genetics is commonly used to identify and …

Cryptococcus neoformans is a pathogenic fungus responsible for serious disease in
immunocompromised individuals. This organism has recently been developed as an …

RNA interference (RNAi) is an experimental technique used to suppress individual gene
expression in eukaryotic cells in a sequence-dependent manner. The process relies on …

While the fungal pathogen Cryptoccocus neoformans is a leading cause of death in
immunocompromised individuals, the molecular toolkit currently available to study this …

Reverse genetics is commonly used to identify and characterize genes involved in a variety
of cellular processes. There is a limited set of positive selectable markers available for use in …

Cryptococcus neoformans is an opportunistic fungal pathogen with a defined sexual cycle
for which genetic and molecular techniques are well developed. The entire genome …

Cryptococcus neoformans infections cause approximately 15% of AIDS-related deaths
owing to a combination of limited antifungal therapies and drug resistance. A collection of …

Cryptococcus neoformans has become a common central nervous system pathogen as the
immunocompromised populations enlarge world-wide. This encapsulated yeast has …

Cryptococcus neoformans is an opportunistic fungal pathogen, which causes life‐
threatening meningoencephalitis in immunocompromised individuals and is responsible for …