Fibrosis is a characteristic feature of all forms of chronic kidney disease. Deposition of
pathological matrix in the interstitial space and within the walls of glomerular capillaries as …

Renal fibrosis is characterized by excessive deposition of extracellular matrix (ECM),
leading to destruction of normal kidney architecture and loss of renal function. The activation …

Fibrosis is the common end point of chronic kidney disease. The persistent production of
inflammatory cytokines and growth factors leads to an ongoing process of extracellular …

Renal fibrosis is a common characteristic of chronic kidney disease (CKD). Aberrant and
excessive depositions of extracellular matrix (ECM) proteins in both glomeruli and interstitial …

Obstructive nephropathy is a major cause of renal failure, particularly in newborn babies and
children. After urinary tract obstruction, and under the influence of mechanical forces and …

Chronic kidney disease, defined as loss of kidney function for more than three months, is
characterized pathologically by glomerulosclerosis, interstitial fibrosis, tubular atrophy …

Fibrotic disorders are commonplace, take many forms and can be life-threatening. No better
example of this exists than the progressive fibrosis that accompanies all chronic renal …

Tubulointerstitial fibrosis is a chronic and progressive process affecting kidneys during aging
and in chronic kidney disease (CKD), regardless of cause. CKD and renal fibrosis affect half …

Renal fibrosis is a major hallmark of chronic kidney disease that is considered to be a
common end point of various types of renal disease. To date, the biological meaning of …

Renal fibrosis is a common consequence and often a central feature of all the progressive
renal diseases that lead to end-stage renal failure. In comparison to wound healing, during …