Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, and
the imbalance between autoimmunity and immune tolerance is considered to be the key …

Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disorder
of the CNS. The etiology of MS remains unknown. However, it is well established that …

Multiple exogenous signals received from cell surface molecules or cytokines play a
significant role in altering the host immune response. In chronic autoimmune‐mediated …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system. Although the precise etiology of MS remains unclear, CD4+ T cells have been …

T lymphocytes play a central role in the pathogenesis of multiple sclerosis (MS)(Zhang et al.,
1992). Both CD4+ and CD8+ T cells have been demonstrated in MS lesions, with CD4+ T …

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system
characterized by focal demyelination patches associated with inflammatory infiltrates …

Multiple sclerosis (MS) is a multifocal demyelinating disease of the central nervous system
pathologically characterized by lesions of infiltrating macrophages and T cells. Multiple lines …

Introduction Multiple sclerosis (MS) is a complex genetic disease characterized by chronic
inflammation of the central nervous system (CNS). The pathology of MS is largely attributed …

Multiple sclerosis (MS) has long been considered a CD4 T-cell disease, primarily because
of the findings that the strongest genetic risk for MS is the major histocompatibility complex …

Multiple sclerosis (MS) is a demyelinating inflammatory disorder of the central nervous
system (CNS), which involves autoimmune responses to myelin antigens. Studies in …