By virtue of its tissue-specific expression, carcinoembryonic antigen (CEA) is an important
self, tumor-associated antigen, which is expressed by different human adenocarcinomas …

Carcinoembryonic antigen (CEA) is a tumor-associated antigen targeted for the
development of colorectal tumor vaccines. In this study, we developed papillomavirus …

Carcinoembryonic antigen (CEA) is a tumor marker for the most common forms of
adenocarcinomas. We have previously described C57BL/6 mice transgenic for the complete …

A new murine model of human colorectal cancer was generated by crossing human
carcinoembryonic antigen (CEA) transgenic mice (H-2Kb) with adenomatous polyposis coli …

Many antigens associated with human tumors are overexpressed in tumor cells as
compared with normal tissues; these “self” tumor-associated antigens are also expressed …

Purpose: Many current clinical trials involve vaccination of patients with vaccines directed
against tumor-associated antigens, which are, in actuality,“self-antigens” overexpressed in …

Purpose: Cancer vaccines targeting tumor-associated antigens are being investigated for
the therapy of tumors. Numerous strategies, including the direct intratumoral (it) vaccination …

In recent years, investigators have carried out several studies designed to evaluate whether
human tumor-associated antigens might be exploited as targets for active specific …

Mice transgenic for the human carcinoembryonic antigen (CEA) gene were prepared for use
as a preclinical model for immunotherapy. A 32.6-kb fragment containing the complete …

Abstract Interleukin-2 (IL-2) has been an effective immune modulator in several active-
specific immunotherapy experimental protocols using either viral or oncolysate-based …