Identification of the serrated neoplasia pathway has improved our understanding of the
pathogenesis of colorectal cancer (CRC). Insights include an increased recognition of the …

Hyperplastic polyps (HPs) of the colon and rectum were historically thought not to be
associated with an increased risk of development of colorectal cancer (CRC). The …

Background and study aims: In routine practice, colonoscopy may fail to prevent colorectal
cancer (CRC), especially in the proximal colon. A better endoscopic recognition of serrated …

BACKGROUND & AIMS: There is evidence that serrated polyps (serrated adenomas and
hyperplastic polyps) have different malignant potential than traditional adenomas. We used …

There is now strong evidence for an alternative pathway of colorectal carcinogenesis
implicating hyperplastic polyps and serrated adenomas. This article briefly reviews the …

Sessile serrated adenoma/polyps (SSA/Ps) are early precursor lesions in the serrated
neoplasia pathway, which results in colorectal carcinomas with BRAF mutations, methylation …

Conventional adenomas have historically been considered to be the only screening-
relevant colorectal cancer (CRC) precursor lesion. The prevailing paradigm was that most …

Colorectal polyps have been traditionally classified as either hyperplastic or adenomatous,
with only the latter progressing to carcinoma. However, it is now recognized that certain …

Background and study aims: Evidence has accumulated that approximately 15% to 30% of
colorectal cancers (CRC) arise from serrated polyps (SP). Population screening, therefore …

METHODS: We collected endoscopy and pathology data on CRCs and polyps of patients
with SPS under treatment in our center. Our primary end point was the proportion of BRAF …