The lens of the eye is one of the most radiosensitive tissues. Although the exact mechanism
of radiation-induced cataract development remains unknown, altered proliferation …

Lens epithelial cell proliferation and differentiation are naturally well regulated and
controlled, a characteristic essential for lens structure, symmetry and function. The effect of …

Cataract is the leading cause of visual impairment which can result in blindness. Cataract
formation has been associated with radiation exposure; however, the mechanistic …

Long duration spaceflight (LDSF) exposes atronauts to radiation including solar particle
events (SPE) and galactic cosmic rays (GCR)(Fig. 1). SPE are released by our Sun and this …

Abstract Purpose: The International Commission on Radiological Protection (ICRP) recently
recommended reducing the occupational equivalent dose limit for the lens of the eye. Based …

Recent epidemiological findings and reanalysis of historical data suggest lens opacities
resulting from ionizing radiation exposures are likely induced at lower doses than previously …

Purpose: Epidemiological evidence regarding the radiosensitivity of the lens of the eye and
radiation cataract development has led to changes in the EU Basic Safety Standards for …

Purpose This study was directed to assess the DNA damage and DNA repair response to X-
ray inflicted lens oxidative damage and to investigate the subsequent changes in lens …

Over the past century, ionizing radiation has been known to induce cataracts in the
crystalline lens of the eye, but its mechanistic underpinnings remain incompletely …

The influence of dose rate on radiation cataractogenesis has yet to be extensively studied.
One recent epidemiological investigation suggested that protracted radiation exposure …