[HTML][HTML] Identification of Frataxin as a regulator of ferroptosis

J Du, Y Zhou, Y Li, J Xia, Y Chen, S Chen, X Wang… - Redox biology, 2020 - Elsevier
Ferroptosis is a newly discovered form of non-apoptotic regulated cell death and is
characterized by iron-dependent and lipid peroxidation. Due to the enhanced dependence …

Ferroptosis: molecular mechanisms and health implications

D Tang, X Chen, R Kang, G Kroemer - Cell research, 2021 - nature.com
Cell death can be executed through different subroutines. Since the description of
ferroptosis as an iron-dependent form of non-apoptotic cell death in 2012, there has been …

The diversified role of mitochondria in ferroptosis in cancer

Y Liu, S Lu, L Wu, L Yang, L Yang, J Wang - Cell death & disease, 2023 - nature.com
Ferroptosis is a form of regulated cell death induced by iron-dependent lipid peroxidation,
and it has been studied extensively since its discovery in 2012. Induced by iron overload …

The protective role of mitochondrial ferritin on erastin-induced ferroptosis

YQ Wang, SY Chang, Q Wu, YJ Gou, L Jia… - Frontiers in aging …, 2016 - frontiersin.org
Ferroptosis, a newly identified form of regulated cell death, is characterized by
overwhelming iron-dependent accumulation of lethal lipid reactive oxygen species (ROS) …

Focus on ferroptosis regulation: exploring novel mechanisms and applications of ferroptosis regulator

TL Ma, JX Chen, P Zhu, CB Zhang, Y Zhou, JX Duan - Life Sciences, 2022 - Elsevier
Ferroptosis is a kind of iron-dependent regulatory necrosis characterized by the fatal
accumulation of iron-dependent lipid peroxides in the plasma membrane and the final …

Ferroptosis and its potential role in human diseases

C Han, Y Liu, R Dai, N Ismail, W Su, B Li - Frontiers in pharmacology, 2020 - frontiersin.org
Ferroptosis is a novel regulated cell death pattern discovered when studying the mechanism
of erastin-killing RAS mutant tumor cells in 2012. It is an iron-dependent programmed cell …

Ferroptosis: Biochemistry and biology in cancers

Z Shi, L Zhang, J Zheng, H Sun, C Shao - Frontiers in oncology, 2021 - frontiersin.org
The challenge of eradicating cancer is that cancer cells possess diverse mechanisms to
protect themselves from clinical strategies. Recently, ferroptosis has been shown to exhibit …

The mechanism of ferroptosis and applications in tumor treatment

X Lin, J Ping, Y Wen, Y Wu - Frontiers in Pharmacology, 2020 - frontiersin.org
Iron-dependent ferroptosis is a new form of cell death in recent years, which is driven by lipid
peroxidation. The lethal lipid accumulation caused by glutathione depletion or inactivation of …

Ferroptosis as a potential target for cancer therapy

Z Chen, W Wang, SR Abdul Razak, T Han… - Cell death & …, 2023 - nature.com
Ferroptosis is a recently discovered essential type of cell death that is mainly characterized
by iron overload and lipid peroxidation. Emerging evidence suggests that ferroptosis is a …

Iron metabolism in ferroptosis

X Chen, C Yu, R Kang, D Tang - Frontiers in cell and developmental …, 2020 - frontiersin.org
Ferroptosis is a form of regulated cell death that is characterized by iron-dependent
oxidative damage and subsequent plasma membrane ruptures and the release of damage …