The role of CETP inhibition in dyslipidemia
K El Harchaoui, WA van der Steeg, ESG Stroes… - Current atherosclerosis …, 2007 - Springer
Cholesteryl ester transfer protein (CETP) inhibitors are currently being investigated because
of their ability to increase high-density lipoprotein cholesterol levels. In various metabolic …
of their ability to increase high-density lipoprotein cholesterol levels. In various metabolic …
Raising high-density lipoprotein with cholesteryl ester transfer protein inhibitors
RW Clark - Current opinion in pharmacology, 2006 - Elsevier
Cholesteryl ester transfer protein (CETP) catalyzes the transfer of cholesteryl ester from high-
density lipoprotein (HDL) to apolipoprotein B-containing lipoproteins in exchange for …
density lipoprotein (HDL) to apolipoprotein B-containing lipoproteins in exchange for …
Targeting cholesteryl ester transfer protein for the prevention and management of cardiovascular disease
PJ Barter, JJP Kastelein - Journal of the American College of Cardiology, 2006 - jacc.org
Epidemiologic studies have shown that the concentration of high-density lipoprotein
cholesterol (HDL-C) is a strong, independent, inverse predictor of coronary heart disease …
cholesterol (HDL-C) is a strong, independent, inverse predictor of coronary heart disease …
Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk
Human and rabbit plasma contain a cholesteryl ester transfer protein (CETP) that promotes
net mass transfers of cholesteryl esters from high density lipoproteins (HDL) to other plasma …
net mass transfers of cholesteryl esters from high density lipoproteins (HDL) to other plasma …
The DEFINE study: a bright future for CETP inhibitors?
N Katsiki, VG Athyros, DP Mikhailidis - Expert Opinion on …, 2011 - Taylor & Francis
Cholesteryl ester transfer protein (CETP) modulates the transfer of triglycerides and
cholesteryl esters between high-density lipoprotein (HDL) and other lipoproteins fractions …
cholesteryl esters between high-density lipoprotein (HDL) and other lipoproteins fractions …
Cholesteryl ester transfer protein (CETP) inhibitors: is there life after torcetrapib?
H Neeli, DJ Rader - Cardiology clinics, 2008 - Elsevier
Despite tremendous progress made in the management of CHD, a significant number of
fatal and nonfatal CHD events still occur, which leads researchers to target other modifiable …
fatal and nonfatal CHD events still occur, which leads researchers to target other modifiable …
CETP inhibition: does the future look promising?
PP Toth - Current cardiology reports, 2011 - Springer
Based on epidemiologic studies conducted throughout the world, it is established that there
is an inverse relationship between high-density lipoprotein cholesterol (HDL-C) and risk for …
is an inverse relationship between high-density lipoprotein cholesterol (HDL-C) and risk for …
Cholesteryl ester transfer protein inhibitors as high-density lipoprotein raising agents
H Shinkai - Expert Opinion on Therapeutic Patents, 2009 - Taylor & Francis
Background: Not only hypercholesterolemia, but also low levels of high-density lipoprotein
cholesterol is a critical risk factor for atherosclerosis-related disease. Therefore, there has …
cholesterol is a critical risk factor for atherosclerosis-related disease. Therefore, there has …
Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases
H Shinkai - Vascular health and risk management, 2012 - Taylor & Francis
Elevated low-density lipoprotein (LDL) cholesterol and lowered high-density lipoprotein
(HDL) cholesterol are important risk factors for cardiovascular disease. Accordingly, raising …
(HDL) cholesterol are important risk factors for cardiovascular disease. Accordingly, raising …
The hypertension peril: lessons from CETP inhibitors
M Hermann, FT Ruschitzka - Current hypertension reports, 2009 - Springer
Pharmacologic inhibitors of the cholesteryl ester transfer protein (CETP) are capable of
increasing HDL cholesterol by 50% to 100% in humans. Despite intriguing antiatherogenic …
increasing HDL cholesterol by 50% to 100% in humans. Despite intriguing antiatherogenic …