Despite the availability of M ycobacterium tuberculosis (Mtb) drugs for over 50 years,
tuberculosis (TB) remains at pandemic levels. New drugs are urgently needed for resistant …

The emergence and spread of drug-resistant strains of Mycobacterium tuberculosis is
worsening the global threat of tuberculosis (TB). There is a need and urgency for the …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, remains a global
health threat despite recent advances and insights into host-pathogen interactions and the …

Tuberculosis (TB) maintains its infamous status regarding its detrimental effect on global
health, causing the highest mortality by a single infectious agent. The presence of resistance …

Mycobacterium tuberculosis (Mtb) has coevolved with a human host to evade and exploit the
immune system in multiple ways. Mtb is an enormously successful human pathogen that can …

Tuberculosis (TB) is a highly contagious bacterial infection caused by Mycobacterium
tuberculosis (Mtb), which has been ranked as the second leading cause of death worldwide …

Abstract Treatment of multidrug-resistant tuberculosis (MDR-TB) is extremely challenging
due to the virulence of the etiologic strains of Mycobacterium tuberculosis (M. tb), the …

Tuberculosis (TB) is one of the leading causes of mortality and morbidity, particularly in
developing countries, presenting a major threat to the public health. The currently …

Tuberculosis (TB) is one of the leading causes of death worldwide, consistently threatening
public health. Conventional tuberculosis treatment requires a long-term treatment regimen …

New therapeutics to augment current approaches and shorten treatment duration are of
critical importance for combating tuberculosis (TB), especially those with novel mechanisms …