In this study, we investigated the molecular mechanisms underlying the ATP analogue
adenosine-5′-O-(3-thio) triphosphate–induced nucleocytoplasmic shuttling of the mRNA …

RNA binding proteins (RBPs) interact with primary, precursor, and mature microRNAs
(miRs) to influence mature miR levels, which in turn affect critical aspects of human …

The human embryonic lethal abnormal vision-like protein, HuR, is a member of the Hu family
of RNA-binding proteins. Over the past decade, this ubiquitously expressed protein has …

MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) act with the Argonaute family of
proteins to regulate target messenger RNAs (mRNAs) posttranscriptionally. SiRNAs typically …

MicroRNAs (miRNAs) are versatile, post-transcriptional regulators of gene expression.
Canonical miRNAs are generated through the two-step DROSHA-and DICER-mediated …

Posttranscriptional regulation is a critical control point for the expression of genes that
promote or retard tumor growth. We previously found that the mRNA-binding protein, ELAV 1 …

Expression of many proto‐oncogenes, cytokines and lymphokines is regulated by targeting
their messenger RNAs for rapid degradation. Essential signals for this control are AU‐rich …

HuR is a ubiquitous RNA-binding protein (RBP) that associates with many mRNAs encoding
proliferative proteins. Although predominantly nuclear, HuR translocation to the cytoplasm is …

MicroRNAs (miRNAs) are small non-coding RNAs (∼ 22 nucleotides) regulating gene
expression at the post-transcriptional level. By directing the RNA-induced silencing complex …

MicroRNA (miRNA) binds to the 3′-UTR of its target mRNAs to repress protein synthesis.
Extensive research was done to understand the mechanism of miRNA-mediated repression …