Aim: Recent evidence indicates that neuroinflammation and oxidative stress play vital roles
in the pathological process of major depressive disorder (MDD). Cinnamic acid (CA), a …

Microglial activation elicits an immune response by producing proinflammatory modulators
and cytokines that cause neurodegeneration. Therefore, a plausible strategy to prevent …

Activation of microglia is a hallmark of neuroinflammation and has been implicated in the
development of many psychiatric disorders. Hydrogen sulfide (H 2 S); a gasotransmitter has …

Accumulating evidence has accrued demonstrating that inflammatory processes in the
central nervous system (CNS) are associated with various neurological disorders including …

Backgrounds: Abundant reports indicate that neuroinflammatory signaling contributes to
behavioral complications associated with depression and may be related to treatment …

Magnolol, the main constituent of Magnolia officinalis, has been shown to produce
antidepressant-like effect in rodents. Growing evidence shows that neuroinflammation …

Introduction Depression is one of the most common neuropsychiatric illnesses which leads
to a huge social and economic burden on modern society. So, it is necessary to develop an …

Emerging evidence suggests an association of Alzheimer's Disease (AD) with microglial and
astrocytic dysregulation. Recent studies have proposed that activated microglia can …

Aims Baicalin (BAI), a flavonoid compound isolated from the root of Scutellaria baicalensis
Georgi, has been established to have potent anti‐inflammation and neuroprotective …

Activated microglial cells play an important role in immune and inflammatory responses in
CNS and play a role in neurodegenerative diseases. We examined the effects of lipoic acid …