[HTML][HTML] What can you see with imaging in pharmaceutical research?

ZR Lu - Molecular Pharmaceutics, 2006 - ACS Publications
The pharmaceutical research community has had a longstanding guideline that for
experimental therapeutic preclinical studies at least six animals are required for each data …

Applications of molecular imaging in drug discovery and development process

BC Ahn - Current Pharmaceutical Biotechnology, 2011 - ingentaconnect.com
The process of drug discovery and development requires enormous resources and time,
with increasing cost for new drug development. Molecular imaging techniques have …

Application of molecular imaging technologies in antitumor drug development and therapy

Y Lin, ZY Chen, F Yang, JS Zhang… - Current …, 2015 - ingentaconnect.com
Molecular imaging enables noninvasive characterization, quantification and visualization of
biological and pathological processes in vivo at cellular and molecular level. It plays an …

[HTML][HTML] In vivo Imaging in Pharmacological Research

N Beckmann, IA Kaltashov, AD Windhorst - Frontiers in pharmacology, 2017 - frontiersin.org
The discovery and development of a biologically active molecule with therapeutic properties
is an increasingly complex task, highly unpredictable at the early stages and frequently …

Application of biomedical imaging in drug discovery and development

ZR Lu - Pharmaceutical Research, 2007 - Springer
Drug discovery and development is a time-consuming and costly process, which may take
approximately 15 years to advance from laboratory discovery to FDA approval and require …

[PDF][PDF] Medical imaging in drug discovery, Part I

AJ Sinskey, SN Finkelstein, SM Cooper - PharmaGenomics. March/April, 2004 - mit.edu
While economic, scientific and regulatory questions still need to be answered, imaging
technologies have the potential to increase efficiencies in many areas of drug research. This …

Technology Insight: novel imaging of molecular targets is an emerging area crucial to the development of targeted drugs

WA Weber, J Czernin, ME Phelps… - Nature clinical practice …, 2008 - nature.com
Targeted drugs hold great promise for the treatment of malignant tumors; however, there are
several challenges for efficient evaluation of these drugs in preclinical and clinical studies …

Molecular imaging in drug development

JK Willmann, N Van Bruggen, LM Dinkelborg… - Nature reviews Drug …, 2008 - nature.com
Molecular imaging can allow the non-invasive assessment of biological and biochemical
processes in living subjects. Such technologies therefore have the potential to enhance our …

[HTML][HTML] Perspectives on molecular and anatomical imaging in drug discovery

MD Silva, M Johnson, D Cvet, R Robertson… - …, 2005 - Taylor & Francis
The role of medical imaging in the preclinical, pharmaceutical environment has entered a
growth phase in the drug discovery setting due to at least three main factors:(i) improved …

Translational molecular imaging in drug development: current status and challenges

M Tian, MJ Welch - Current Medical Imaging, 2010 - ingentaconnect.com
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems. In the …