Similarities and differences between the effects of EPA and DHA on markers of atherosclerosis in human subjects

DS Kelley, Y Adkins - Proceedings of the Nutrition Society, 2012 - cambridge.org
We have reviewed effects of long chain (LC) n-3 PUFA on markers of atherosclerosis in
human subjects with a focus on individual effects of EPA and DHA. Initial results from …

[HTML][HTML] Effect of low doses of long-chain n− 3 PUFAs on endothelial function and arterial stiffness: a randomized controlled trial

TAB Sanders, WL Hall, Z Maniou, F Lewis… - The American journal of …, 2011 - Elsevier
Background: The dietary intake of n− 3 (omega-3) long-chain PUFAs (LC-PUFAs) from fish
may improve endothelial function and arterial stiffness. Objective: The objective was to test …

The differential effects of EPA and DHA on cardiovascular risk factors

SC Cottin, TA Sanders, WL Hall - Proceedings of the Nutrition Society, 2011 - cambridge.org
Compelling evidence exists for the cardioprotective benefits resulting from consumption of
fatty acids from fish oils, EPA (20: 5n-3) and DHA (22: 6n-3). EPA and DHA alter membrane …

n-3 PUFA in CVD: influence of cytokine polymorphism

C Von Schacky - Proceedings of the Nutrition Society, 2007 - cambridge.org
In their current guidelines cardiac societies recommend the consumption of the two n-3 fatty
acids EPA and DHA to prevent cardiovascular complications. Cardiovascular events are …

Variability in the Clinical Effects of the Omega-3 Polyunsaturated Fatty Acids DHA and EPA in Cardiovascular Disease—Possible Causes and Future Considerations

C Michaeloudes, S Christodoulides, P Christodoulou… - Nutrients, 2023 - mdpi.com
Cardiovascular disease (CVD) that includes myocardial infarction and stroke, is the leading
cause of mortality worldwide. Atherosclerosis, the primary underlying cause of CVD, can be …

Protective role of n6/n3 PUFA supplementation with varying DHA/EPA ratios against atherosclerosis in mice

L Liu, Q Hu, H Wu, Y Xue, L Cai, M Fang, Z Liu… - The Journal of nutritional …, 2016 - Elsevier
The effects of n3 polyunsaturated fatty acids (PUFA) on cardiovascular disease are
controversial. We currently explored the effects of various ratios of docosahexaenoic acid …

Ethnicity, plasma phospholipid fatty acid composition and inflammatory/endothelial activation biomarkers in the Multi-Ethnic Study of Atherosclerosis (MESA)

BT Steffen, LM Steffen, R Tracy, D Siscovick… - European journal of …, 2012 - nature.com
RESULTS: Chinese adults were found to have the highest mean levels of plasma
eicosapentaenoic acid (EPA, 1.24%) and docosahexaenoic acid (DHA, 4.95%), and the …

[HTML][HTML] (n-3) fatty acids and cardiovascular health: are effects of EPA and DHA shared or complementary?

D Mozaffarian, JHY Wu - The Journal of nutrition, 2012 - Elsevier
Considerable research supports cardiovascular benefits of consuming omega-3 PUFA, also
known as (n-3) PUFA, from fish or fish oil. Whether individual long-chain (n-3) PUFA have …

The effect of EPA and DHA on metabolic syndrome patients: a systematic review of randomised controlled trials

E Lopez-Huertas - British journal of nutrition, 2012 - cambridge.org
Metabolic syndrome (MS) is characterised by accumulation of CVD risk factors. The use of
very long chain n-3 polyunsaturated fatty acids (VLC n3 PUFA) could potentially benefit MS …

Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages

JE McLaren, DR Michael, IA Guschina, JL Harwood… - Lipids, 2011 - Springer
There is evidence that long chain n-3 PUFA (such as from fish oils) provide atheroprotection
through, in part, changes in macrophage function although it has not been fully determined …