Acetaminophen (APAP)-induced liver injury (AILI) is the main cause of acute liver failure in
the developed countries. The present study aimed to evaluate the therapeutic efficacy of …

Overuse of acetaminophen (APAP) is a major cause of drug-induced liver failure at the
clinics. Apigenin (API) is a natural flavonoid derived from Matricaria chamomilla. The aim of …

Acetaminophen (APAP) overdose is one of the most common causes of drug‐induced acute
liver failure in humans. To investigate the hepatoprotective effect of salvianolic acid C (SAC) …

Background Acetaminophen (paracetamol, APAP) overdose is the principal cause of acute
liver injury (ALI) that leads to liver failure typified with oxidative stress, mitochondrial and …

Cardamonin (CD), a naturally occurring chalcone derived from the Alpinia species, has
been shown to exert antioxidant and anti-inflammatory activity, but its role in the prevention …

Acetaminophen (APAP) overdose-induced fatal hepatotoxicity is majorly characterized by
overwhelmingly increased oxidative stress while enhanced nuclear factor-erythroid 2 …

Acetaminophen (APAP) overdose is the main cause of acute liver failure. Apigenin (API) is a
natural dietary flavonol with high antioxidant capacity. Herein, we investigated protection by …

The vast majority of drug-induced liver injury is mainly attributed to acetaminophen (APAP)
overdose. Salvianolic acid A (Sal A), a powerful water-soluble compound obtained from …

The activated c-Jun N-terminal kinase (JNK) specifically combined with SH3 domain-binding
protein 5 (Sab) may mediate damage to the mitochondrial respiratory chain. Whether …

Acetaminophen (APAP)-induced liver injury is a common hepatic disease resulting from
drug abuse. Few targeted treatments are available clinically nowadays. The flower bud of …