Effect of intravenous fluid treatment with a balanced solution vs 0.9% saline solution on mortality in critically ill patients: the BaSICS randomized clinical trial
Importance Intravenous fluids are used for almost all intensive care unit (ICU) patients.
Clinical and laboratory studies have questioned whether specific fluid types result in …
Clinical and laboratory studies have questioned whether specific fluid types result in …
Effect of slower vs faster intravenous fluid bolus rates on mortality in critically ill patients: the basics randomized clinical trial
Importance Slower intravenous fluid infusion rates could reduce the formation of tissue
edema and organ dysfunction in critically ill patients; however, there are no data to support …
edema and organ dysfunction in critically ill patients; however, there are no data to support …
Balanced crystalloids versus saline in critically ill adults—a systematic review with meta-analysis
Background The comparative efficacy and safety of balanced crystalloid solutions and saline
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …
Effect of a buffered crystalloid solution vs saline on acute kidney injury among patients in the intensive care unit: the SPLIT randomized clinical trial
Importance Saline (0.9% sodium chloride) is the most commonly administered intravenous
fluid; however, its use may be associated with acute kidney injury (AKI) and increased …
fluid; however, its use may be associated with acute kidney injury (AKI) and increased …
Balanced crystalloids versus saline for critically ill patients (BEST-Living): a systematic review and individual patient data meta-analysis
Background The effect of balanced crystalloids compared with that of saline in critically ill
patients overall and in specific subgroups is unclear. We aimed to assess whether use of …
patients overall and in specific subgroups is unclear. We aimed to assess whether use of …
Association between type of fluid received prior to enrollment, type of admission, and effect of balanced crystalloid in critically ill adults: a secondary exploratory …
FG Zampieri, FR Machado, RS Biondi… - American Journal of …, 2022 - atsjournals.org
Rationale: The effects of balanced crystalloid versus saline on clinical outcomes for ICU
patients may be modified by the type of fluid that patients received for initial resuscitation …
patients may be modified by the type of fluid that patients received for initial resuscitation …
Balanced crystalloids versus saline in critically ill adults
Background Both balanced crystalloids and saline are used for intravenous fluid
administration in critically ill adults, but it is not known which results in better clinical …
administration in critically ill adults, but it is not known which results in better clinical …
Resuscitation fluid types in sepsis, surgical, and trauma patients: a systematic review and sequential network meta-analyses
Background Crystalloids and different component colloids, used for volume resuscitation,
are sometimes associated with various adverse effects. Clinical trial findings for such fluid …
are sometimes associated with various adverse effects. Clinical trial findings for such fluid …
Fluid therapy for critically ill adults with sepsis: a review
Importance Approximately 20% to 30% of patients admitted to an intensive care unit have
sepsis. While fluid therapy typically begins in the emergency department, intravenous fluids …
sepsis. While fluid therapy typically begins in the emergency department, intravenous fluids …
Intravenous fluid therapy in critically ill adults
Intravenous fluid therapy is one of the most common interventions in acutely ill patients.
Each day, over 20% of patients in intensive care units (ICUs) receive intravenous fluid …
Each day, over 20% of patients in intensive care units (ICUs) receive intravenous fluid …